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Merck

EMU014681

MISSION® esiRNA

targeting mouse Ezh2

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UNSPSC-Code:
41105324
NACRES:
NA.51

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Beschreibung

Powered by Eupheria Biotech

Produktlinie

MISSION®

Form

lyophilized powder

esiRNA cDNA-Zielsequenz

CTGTTCAGAGGGAGCAAAGCTTGCATTCATTTCATACGCTCTTCTGTCGACGATGTTTTAAGTATGACTGCTTCCTACATCCCTTCCATGCAACACCCAACACATATAAGAGGAAGAACACAGAAACAGCTTTGGACAACAAGCCTTGTGGACCACAGTGTTACCAGCATCTGGAGGGAGCTAAGGAGTTTGCTGCTGCTCTTACTGCTGAGCGTATAAAGACACCACCTAAACGCCCAGGGGGGCGCAGAAGAGGAAGACTTCCGAATAACAGTAGCAGACCCAGCACCCCCACCATCAGTGTGCTGGAGTCAAAGGATACAGACAGTGACAGAGAAGCAGGGACTGAAACTGGGGGAGAGAACAATGATAAAGAAGAAGAAGAGAAAAAAGATGAGACGTCCAGCTCCTCTGAAGCAAATTCTCGG

Ensembl | Maus Hinterlegungsnummer

ENSMUSG00000029687

NCBI-Hinterlegungsnummer

NM_001146689

Versandbedingung

ambient

Lagertemp.

−20°C

Angaben zum Gen

mouse ... EZH2(14056), Ezh2(14056)

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1 of 4

Dieser Artikel
EMU151771EMU026001EMU092661
MISSION® esiRNA targeting mouse Ezh2

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EMU014681

MISSION® esiRNA

MISSION® esiRNA targeting mouse Ezh1

Sigma-Aldrich

EMU151771

MISSION® esiRNA

MISSION® esiRNA targeting mouse Fscn1

Sigma-Aldrich

EMU026001

MISSION® esiRNA

MISSION® esiRNA targeting mouse Fen1

Sigma-Aldrich

EMU092661

MISSION® esiRNA

esiRNA cDNA target sequence

CTGTTCAGAGGGAGCAAAGCTTGCATTCATTTCATACGCTCTTCTGTCGACGATGTTTTAAGTATGACTGCTTCCTACATCCCTTCCATGCAACACCCAACACATATAAGAGGAAGAACACAGAAACAGCTTTGGACAACAAGCCTTGTGGACCACAGTGTTACCAGCATCTGGAGGGAGCTAAGGAGTTTGCTGCTGCTCTTACTGCTGAGCGTATAAAGACACCACCTAAACGCCCAGGGGGGCGCAGAAGAGGAAGACTTCCGAATAACAGTAGCAGACCCAGCACCCCCACCATCAGTGTGCTGGAGTCAAAGGATACAGACAGTGACAGAGAAGCAGGGACTGAAACTGGGGGAGAGAACAATGATAAAGAAGAAGAAGAGAAAAAAGATGAGACGTCCAGCTCCTCTGAAGCAAATTCTCGG

esiRNA cDNA target sequence

CTGCTCAATAGCCAGGCTTCTGGGGACAAAGACATGCAAGCAGGTCTTTCAGTTTGCAGTCAAAGAATCACTTATCCTAAAGCTGCCAACAGATGAGCTCATGAACCCTGCACAGAAGAAGAAAAGAAAACACAGGTTGTGGGCCGCACACTGCAGGAAAATTCAGCTGAAGAAAGATAACAATTCTACACAAGTGTATAACTACCAACCCTGTGACCACCCAGACCGTCCGTGTGACAGCACATGCCCCTGCATCATGACCCAGAACTTTTGTGAAAAGTTCTGCCAGT

esiRNA cDNA target sequence

AATGGACCTGTCAGCCAATCAGGATGAAGAGACCGATCAGGAGACCTTCCAGCTGGAGATCGACCGCGACACAAGAAAGTGTGCCTTTCGCACCCACACGGGCAAGTACTGGACACTGACGGCGACCGGAGGTGTGCAATCCACTGCGTCCACCAAGAACGCCAGCTGCTACTTTGACATCGAGTGGTGTGACCGCCGGATCACTCTGAGAGCCTCCAACGGCAAGTTTGTGACCGCCAAGAAAAATGGCCACGTGGCCGCCTCGGTGGAGACAGCAGGGGACTCGGAACTCTTCCTCATGAAGCTGATTAACCGCCCCATCATTGCGTTCCGGGGGGAACACGGGTTCATTGCGTGCCGCAAGGTCACGGGCACTCTGGATGCCAACCGTTCCAGTTACGATGTCTTCCAGTTGGAATTCAATGACGGCGCCTACAACATCAAAGACTCCACGGG

esiRNA cDNA target sequence

TCTGCTCCGAACATTCCTCTTCGCCGGTAGGAAGAAGCCATTGCTCCTGTGCTACCATGGGAATTCACGGCCTTGCCAAACTAATTGCTGATGTGGCCCCCAGTGCCATCCGTGAGAATGACATCAAGAGCTACTTTGGTCGCAAAGTGGCCATCGATGCCTCCATGAGCATCTACCAGTTCCTGATTGCTGTTCGTCAGGGTGGGGATGTGCTGCAGAACGAGGAGGGTGAGACCACCAGCCACCTGATGGGCATGTTCTACCGTACCATCCGCATGATGGAGAATGGCATCAAGCCTGTGTACGTCTTTGATGGCAAACCACCACAGCTGAAGTCAGGCGAGCTGGCCAAGCGCAGTGAGAGGCGCGCCGAGGCTGAGAAGCAACTGCAGCAGGCTCAGGAGGCTGGGATGGAGGAGGAGGTGGAGAAGTTCACCAAGAGGCTCGTGAAGGTCACCAAGCAACACAATGATGAGTGCAAACACCTGCTG

Ensembl | mouse accession no.

ENSMUSG00000029687

Ensembl | mouse accession no.

ENSMUSG00000006920

Ensembl | mouse accession no.

ENSMUSG00000029581

Ensembl | mouse accession no.

ENSMUSG00000024742

Gene Information

mouse ... EZH2(14056), Ezh2(14056)

Gene Information

mouse ... EZH1(14055), Ezh1(14055)

Gene Information

mouse ... Fscn1(14086)

Gene Information

mouse ... FEN1(14156), Fen1(14156)

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

NCBI accession no.

NM_001146689

NCBI accession no.

NM_007970

NCBI accession no.

NM_007984

NCBI accession no.

NP_032025

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

Allgemeine Beschreibung

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Rechtliche Hinweise

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

10 - Combustible liquids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Die Dokumentenbibliothek aufrufen

B C Roy et al.
Oncogene, 34(34), 4519-4530 (2014-12-09)
The enhancer of zeste homolog-2 (EZH2) represses gene transcription through histone H3 lysine-27-trimethylation (H3K27me3). Citrobacter rodentium (CR) promotes crypt hyperplasia and tumorigenesis by aberrantly regulating Wnt/β-catenin signaling. We aimed at investigating EZH2's role in epigenetically regulating Wnt/β-catenin signaling following bacterial
Lu Lu et al.
Toxicology and applied pharmacology, 289(2), 276-285 (2015-09-30)
Lung cancer is regarded as the leading cause of cancer-related deaths, and cigarette smoking is one of the strongest risk factors for the development of lung cancer. However, the mechanisms for cigarette smoke-induced lung carcinogenesis remain unclear. The present study
Ying Qi et al.
Molecular bioSystems, 11(7), 1980-1986 (2015-05-08)
A histone methyltransferase enhancer of zeste homologue 2 (EZH2) catalyzes trimethylation at histone H3 lysine27 (H3K27me3) and is frequently dysregulated in a wide range of human cancers. EZH2-mediated gene silencing contributes to carcinogenesis and regulates stem cell maintenance and differentiation;
Jessica Svedlund et al.
Endocrine-related cancer, 21(2), 231-239 (2013-12-03)
Primary hyperparathyroidism (pHPT) resulting from parathyroid tumors is a common endocrine disorder with incompletely understood etiology. In renal failure, secondary hyperparathyroidism (sHPT) occurs with multiple tumor development as a result of calcium and vitamin D regulatory disturbance. The aim of
Gongchao Wang et al.
American journal of cancer research, 5(10), 3162-3173 (2015-12-23)
Lung adenocarcinoma (LAD) and lung squamous cell cancer (LSCC) are two most common histological types of lung cancer, while they differ in many aspects. Recent evidence shows that long non-coding RNAs (lncRNAs) play an important role in the process of
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