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M9429

Menadion

meets USP testing specifications

Synonym(e):

2-Methyl-1,4-naphthochinon, Vitamin K3

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Über diesen Artikel

Empirische Formel (Hill-System):
C11H8O2
CAS-Nummer:
Molekulargewicht:
172.18
UNSPSC Code:
12352205
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-372-6
Beilstein/REAXYS Number:
1908453
MDL number:
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biological source

synthetic (organic)

Quality Segment

agency

USP/NF, meets USP testing specifications

assay

98.5-101.0% dry basis

form

solid

mp

105-107 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CC1=CC(=O)c2ccccc2C1=O

InChI

1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3

InChI key

MJVAVZPDRWSRRC-UHFFFAOYSA-N

Gene Information

human ... NQO1(1728)

General description

Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets.

Application

Menadione has been used:
  • to treat HL-60 cells as positive control for apoptosis for flow cytometry
  • as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization
  • to treat HaCaT cell line, for quantifying total and oxidised glutathione

Biochem/physiol Actions

Menadione is an oxidative stress inducer.

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Dieser Artikel
M5625477751381006
Menadion United States Pharmacopeia (USP) Reference Standard

USP

1381006

Menadion

description

meets USP testing specifications

description

crystalline

description

analytical standard

description

United States Pharmacopeia (USP) Reference Standard

biological source

synthetic (organic)

biological source

synthetic

biological source

-

biological source

-

assay

98.5-101.0% dry basis

assay

≥98.0% (HPLC)

assay

-

assay

-

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

application(s)

pharmaceutical (small molecule)

form

solid

form

crystalline

form

-

form

-

mp

105-107 °C (lit.)

mp

105-107 °C (lit.)

mp

105-107 °C (lit.)

mp

105-107 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-


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Piktogramme

Exclamation markEnvironment

Signalwort

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Zielorgane

Respiratory system

Lagerklasse

11 - Combustible Solids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

PSA (Persönliche Schutzausrüstung)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Questions

  1. What is the solubility of product M9429, Menadione?

    1 answer
    1. The solubility of product M9429, Menadione, is as follows:

      1.It is soluble in chloroform (100 mg/ml), with heating as needed, yielding a clear to slightly hazy, yellow-green solution.
      2.Menadione is also soluble in DMSO (1 mg/ml) and in ethanol (16 mg/ml).

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