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Ruthenium catalyzed synthesis of 2,3-unsaturated C-glycosides from glycals.

Carbohydrate research (2015-02-16)
Batthula Srinivas, Thurpu Raghavender Reddy, Sudhir Kashyap
ZUSAMMENFASSUNG

A highly efficient and convenient C-glycosylation method was developed using ruthenium(III) chloride for the synthesis of 2,3-unsaturated C-glycosides. Various nucleophiles such as allyl trimethylsilane, triethylsilane, trimethylsilyl cyanide, trimethylsilyl azide and heterocycles such as thiophene and furan reacted smoothly with glycals in the presence of catalytic amount of ruthenium trichloride under mild reaction conditions.

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Produktbeschreibung

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