366919

Chloroform

ACS spectrophotometric grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• Synonym(e): Methylidyntrichlorid, Trichlormethan
• Empirische Formel (Hill-System): CHCl₃
• CAS-Nummer: 67-66-3
• Molekulargewicht: 119.38
• UNSPSC Code: 12191502
• NACRES: NA.04
• PubChem Substance ID: 329755456
• MDL number: MFCD00000826
• Beilstein/REAXYS Number: 1731042
• Grade: ACS spectrophotometric grade
• Assay: ≥99.8%
• Technique(s): UV/Vis spectroscopy: suitable
• Bp: 60.5-61.5 °C (lit.)
• Vapor pressure: 160 mmHg ( 20 °C)

Eigenschaften

• Produktname: Chloroform, ACS spectrophotometric grade, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• SMILES string: ClC(Cl)Cl
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N
• grade: ACS spectrophotometric grade
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• assay: ≥99.8%
• form: liquid
• contains: 0.5-1.0% ethanol as stabilizer
• technique(s): UV/Vis spectroscopy: suitable
• impurities: Acetone and aldehyde, passes test; Acid and chloride, passes test; Free chlorine (Cl), passes test; H₂SO₄, passes test (darkened); <0.03% water
• evapn. residue: <0.001%
• color: APHA: ≤10
• refractive index: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.48 g/mL at 25 °C (with ethanol stabilizer); 1.492 g/mL at 25 °C (lit.)
• cation traces: Pb: ≤0.05 ppm
• λ: H₂O reference
• UV absorption: λ: 245 nm A_max: 1.00; λ: 255 nm A_max: 0.25; λ: 260 nm A_max: 0.15; λ: 270 nm A_max: 0.05; λ: 290-400 nm A_max: 0.01
• Quality Level: 100

Beschreibung

Application

Chloroform (spectrophotometric grade) was used in the following processes:

• Synthesis of colloidal hydrophobic CdSe core nanocrystals (quantum dots).[1]
• Preparing phospholipid solutions.[2]
• As a solvent in the photolysis reaction of ruthenium complexes.[3]

It may be used as:

• Solvent for recrystallization.[4]
• Reference compound to detect the presence of chloroform in Tobacco smokes.[5]
• Extractant in solvent extraction process.[6]

General description

Chloroform is a is a colorless, volatile chlorinated organic solvent whose vapors have narcotic effect.[7] It is susceptible to degradation with time which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Spectrophotometric grade chloroform shows low UV absorption which makes it an ideal solvent for spectrophotometry.

Sicherheitshinweise

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Lagerklasse: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash