L1663

Lidocaine N-ethyl chloride

Name: Lidocaine N-ethyl chloride
Brand: SIGMA
Price: 2924 BRL

sodium channel blocker

Sinônimo(s):

N-(2,6-Dimethylphenylcarbamoylmethyl) triethylammonium chloride

Slide 1 of 1

Faça login para ver os preços organizacionais e de contrato.

Selecione um tamanho

500 MG

R$ 2.924,00

1 G

R$ 5.608,00

R$ 2.924,00

Verificar disponibilidade no carrinho

Peça uma encomenda em massa

Sobre este item

Fórmula empírica (Notação de Hill):

C₁₆H₂₇N₂OCl

Número CAS:

5369-03-9

Peso molecular:

298.85

UNSPSC Code:

12352200

PubChem Substance ID:

24896288

NACRES:

NA.77

MDL number:

MFCD01669894

Quality level:

100

Storage condition:

protect from light

Documentos Principais

Visualizar Toda a Documentação

Pular para

Assistência Técnica

Precisa de ajuda? Nossa equipe de cientistas experientes está à sua disposição.

Estamos aqui para ajudar

Nome do produto

Lidocaine N-ethyl chloride,

SMILES string

[Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C16H26N2O.ClH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H

InChI key

LLPPOMUAOGMYQI-UHFFFAOYSA-N

storage condition

protect from light

solubility

H₂O: soluble

storage temp.

room temp

Quality Level

100

Categorias relacionadas

Bioactive Small Molecules

Comparar Itens Semelhantes

Ver Comparação Total

Mostrar diferenças

1 of 4

Este Item	SML1444	C4382	D2926
Sigma-Aldrich L1663 Lidocaine N-ethyl chloride	Sigma-Aldrich SML1444 (±)-Mepivacaine hydrochloride	Sigma-Aldrich C4382 Carbamoylcholine chloride	Sigma-Aldrich D2926 Diphenyleneiodonium chloride
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 300
storage temp. room temp	storage temp. room temp	storage temp. -	storage temp. room temp
solubility H₂O: soluble	solubility H₂O: 20 mg/mL, clear	solubility H₂O: 1 g/mL, ethanol: 20 mg/mL	solubility DMSO: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
storage condition protect from light	storage condition desiccated	storage condition -	storage condition -

Other Notes

Stable at room temperature lyophilized. In solution, store at 4 °C for up to two weeks. Store solutions at -20 °C for up to six months.

Biochem/physiol Actions

Lidocaine N-ethyl chloride is an intracellular voltage-gated sodium channel blocker.

Classe de armazenamento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Co-Application of Eugenol and QX-314 Elicits the Prolonged Blockade of Voltage-Gated Sodium Channels in Nociceptive Trigeminal Ganglion Neurons.

Sung-Min Hwang et al.

Biomolecules, 10(11) (2020-11-11)

Local anesthetics (LAs) can completely block nociception by inhibiting voltage-gated sodium channels (VGSCs), and thus, blocking action potentials (APs) within sensory neurons. As one of the several LAs, eugenol is used for dental pain treatment. It reportedly features multiple functions

Asymmetry between ON and OFF α ganglion cells of mouse retina: integration of signal and noise from synaptic inputs.

Michael A Freed

The Journal of physiology, 595(22), 6979-6991 (2017-09-16)

Bipolar and amacrine cells presynaptic to the ON sustained α cell of mouse retina provide currents with a higher signal-to-noise power ratio (SNR) than those presynaptic to the OFF sustained α cell. Yet the ON cell loses proportionately more SNR

BDNF-induced presynaptic facilitation of GABAergic transmission in the hippocampus of young adults is dependent of TrkB and adenosine A2A receptors.

Mariana Colino-Oliveira et al.

Purinergic signalling, 12(2), 283-294 (2016-02-22)

Brain-derived neurotrophic factor (BDNF) and adenosine are widely recognized as neuromodulators of glutamatergic transmission in the adult brain. Most BDNF actions upon excitatory plasticity phenomena are under control of adenosine A2A receptors (A2ARs). Concerning gamma-aminobutyric acid (GABA)-mediated transmission, the available

Cell type-specific modulation of sensory and affective components of itch in the periaqueductal gray.

Vijay K Samineni et al.

Nature communications, 10(1), 4356-4356 (2019-09-27)

Itch is a distinct aversive sensation that elicits a strong urge to scratch. Despite recent advances in our understanding of the peripheral basis of itch, we know very little regarding how central neural circuits modulate acute and chronic itch processing.

Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons.

Andrew W Baxter et al.

The European journal of neuroscience, 34(2), 213-220 (2011-07-14)

P2X4 receptors are calcium-permeable cation channels gated by extracellular ATP. They are found close to subsynaptic sites on hippocampal CA1 neurons. We compared features of synaptic strengthening between wild-type and P2X4 knockout mice (21-26 days old). Potentiation evoked by a

Exibir todos os documentos relacionados

Questions

Reviews

No rating value

Active Filters

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica

Lidocaine N-ethyl chloride