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Merck

14927

Serotonin

analytical standard

Sinonimo/i:

3-(2-Aminoethyl)-5-hydroxyindole, 5-HT, 5-Hydroxytryptamine

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25 MG

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C10H12N2O
Numero CAS:
50-67-9
Peso molecolare:
176.22
Beilstein:
143524
Numero CE:
200-058-9
Numero MDL:
MFCD00055054
Codice UNSPSC:
85151701
ID PubChem:
329750658
NACRES:
NA.24

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Grado

analytical standard

Livello qualitativo

100

Descrizione

Drug Control: Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet

Saggio

≥95.0% (HPLC)

Durata

limited shelf life, expiry date on the label

drug control

Kábítószer / Narcotic Drug (Hungary), 78/2022. (XII. 28.) BM rendelet

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Impurezze

≤1.0% water (calc. from elemental analysis)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

OC1=CC=C(NC=C2CCN)C2=C1

InChI

1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
QZAYGJVTTNCVMB-UHFFFAOYSA-N

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1 of 4

Questo articolo
H9523399698H7752
Serotonin analytical standard

Supelco

14927

Serotonin

Serotonina powder

Sigma-Aldrich

H9523

Serotonina

5-Hydroxy-L-tryptophan Serotonin precursor.

Millipore

399698

5-Hydroxy-L-tryptophan

Serotonin creatinine sulfate monohydrate powder

Sigma-Aldrich

H7752

Serotonin creatinine sulfate monohydrate

format

neat

format

-

format

-

format

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

grade

analytical standard

grade

-

grade

-

grade

-

assay

≥95.0% (HPLC)

assay

≥98%

assay

≥98% (HPLC)

assay

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

impurities

≤1.0% water (calc. from elemental analysis)

impurities

-

impurities

-

impurities

-

Descrizione generale

Serotonin, also known as 5-hydroxytryptamine, is an important biogenic monoamine neurotransmitter and a neuromodulator, found in the central nervous system. It is involved in regulating various physiological processes such as appetite, anxiety, sleep, mood, and blood pressure. A decrease in serotonin levels might result in disorders such as obesity, schizophrenia, and depression.

Applicazioni

This analytical standard can also be used as follows:
  • Electrochemical detection of serotonin in urine samples using a glassy carbon electrode (GCE) coated with multiwalled-carbon-nanotubes (MWCNT) doped with nickel, zinc, and iron oxide nanoparticles by a cyclic voltammetry procedure
  • Development and validation of an ultra high-performance liquid chromatography-tandem mass spectrometry method to determine serotonin in raw and roasted samples of a variety of nuts, along with commercial nut products
  • Designing of RuO2 nanowires/CeO2-AuNFs nanofibers/graphene oxide/functionalized multiwalled carbon nanotubes modified screen-printed carbon electrode for the multi-residue analysis of serotonin, dopamine, and ascorbic acid in cerebrospinal fluid and vitamin C tablet samples
  • Construction of a low-cost glassy carbon electrode (GCE) modified with a nanoparticulate film of nanodiamonds and gold nanoparticles anchored to GCE using casein for the quantification of serotonin in urine samples
  • Determination of serotonin in urine samples using a two-dimensional capillary isotachophoresis-capillary zone electrophoresis procedure coupled with tandem mass spectrometry (MS/MS)

Altre note

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301,H361

Classi di pericolo

Acute Tox. 3 Oral - Repr. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
BCCL7170
BCCL5779
BCCJ2894
BCCG9008
BCCF8292

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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Dear Sirs: What is the solubility of standard serotonin? Greetings

    1 answer

    1. This product is not tested for solubility. However, various sources state that Serotonin is generally soluble in methanol, slightly soluble in water, DMSO, and chloroform. The exact concentrations at which it can be solubilized is not determined.

      Helpful?

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