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Merck

EMU060801

MISSION® esiRNA

targeting mouse Stk11

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Informazioni su questo articolo

NACRES:
NA.51
UNSPSC Code:
41105324

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Nome del prodotto

MISSION® esiRNA, targeting mouse Stk11

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GAGAGGCCAACGTCAAGAAGGAGATCCAGCTGCTGCGGCGGCTGCGGCATCGGAATGTGATCCAGCTTGTGGACGTGCTGTACAATGAGGAGAAGCAGAAGATGTATATGGTGATGGAGTACTGCGTATGTGGCATGCAGGAGATGCTGGACAGTGTGCCGGAGAAGCGCTTCCCTGTGTGCCAAGCTCATGGGTACTTCCGCCAGCTGATTGACGGCCTGGAATACCTACACAGCCAGGGCATTGTTCACAAGGACATCAAGCCGGGCAACCTGCTACTCACCACCAATGGCACACTCAAGATCTCCGACCTCGGTGTTGCCGAGGCCCTGCACCCTTTCGCTGTGGATGACACCTGCCGGACAAGCCAGGGCTCCCCGGCCTTCCAGCCTCCTGAGATTG

Ensembl | mouse accession no.

ENSMUSG00000003068

NCBI accession no.

NM_011492

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... STK11(20869), Stk11(20869)

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Questo articolo
EMU008591EMU071711EMU048031
MISSION® esiRNA targeting mouse Stk11

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EMU060801

MISSION® esiRNA

MISSION® esiRNA targeting mouse Sdc1

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EMU008591

MISSION® esiRNA

MISSION® esiRNA targeting mouse Sipa1

Sigma-Aldrich

EMU071711

MISSION® esiRNA

MISSION® esiRNA targeting mouse Stk31

Sigma-Aldrich

EMU048031

MISSION® esiRNA

Ensembl | mouse accession no.

ENSMUSG00000003068

Ensembl | mouse accession no.

ENSMUSG00000020592

Ensembl | mouse accession no.

ENSMUSG00000056917

Ensembl | mouse accession no.

ENSMUSG00000023403

esiRNA cDNA target sequence

GAGAGGCCAACGTCAAGAAGGAGATCCAGCTGCTGCGGCGGCTGCGGCATCGGAATGTGATCCAGCTTGTGGACGTGCTGTACAATGAGGAGAAGCAGAAGATGTATATGGTGATGGAGTACTGCGTATGTGGCATGCAGGAGATGCTGGACAGTGTGCCGGAGAAGCGCTTCCCTGTGTGCCAAGCTCATGGGTACTTCCGCCAGCTGATTGACGGCCTGGAATACCTACACAGCCAGGGCATTGTTCACAAGGACATCAAGCCGGGCAACCTGCTACTCACCACCAATGGCACACTCAAGATCTCCGACCTCGGTGTTGCCGAGGCCCTGCACCCTTTCGCTGTGGATGACACCTGCCGGACAAGCCAGGGCTCCCCGGCCTTCCAGCCTCCTGAGATTG

esiRNA cDNA target sequence

CTGGTGGCTTTCATGCTGTACCGGATGAAGAAGAAGGACGAAGGCAGCTACTCCTTGGAGGAGCCCAAACAAGCCAATGGCGGTGCCTACCAGAAACCCACCAAGCAGGAGGAGTTCTACGCCTGATGGGGAAATAGTTCTTTCTCCCCCCACAGCCCCTGCCACTCACTAGGCTCCCACTTGCCTCTTCTGTGAAAAACTTCAAGCCCTGGCCTCCCCACCACTGGGTCATGTCCTCTGCACCCAGGCCCTTCCAGCTGTTCCTGCCCGAGCGGTCCCAGGGTGTGCTGGGAACTGATTCCCCTCCTTTGACTTCTGCCTAGAAGCTTGGGTGCAAAGGGTTTCTTGCATCTGATCTTTCTACCACAACCACACCTGTTGTCCACTCTTCTGACTTGGTTTCTCCAAATGGGA

esiRNA cDNA target sequence

AAGGTGGCATCCTGTACTGCCGCGCAGGCCAGGGCTCTGAGGAAGAGATGTACAACAACCAGGAGGCCGGAGCAGCCTTTATGCAGTTCCTTACTTTGCTGGGTGATGTGGTGCGACTCAAAGGCTTTGAAAGTTACCGGGCCCAGCTGGATACCAAAACGGATTCCACGGGCACACACTCACTCTACACCACCTACCAAGACCATGAGATCATGTTTCACGTGTCCACGATGCTGCCTTACACGCCTAATAACCAGCAACAGCTCCTGAGGAAGCGTCATATCGGCAACGATATTGTGACCATCGTGTTCCAGGAGCCCGGTAGCAAGCCCTTCTGCCCTACAACAATCCGCTCTCACTTCCAGCACGTTTTCTTGGTGGTGCGTGCGCATGCTCCCTGCACCCCACACACCTCATACAGGGTGGCAGTGA

esiRNA cDNA target sequence

GAGCTGCCTCTGCTGTATCCTGAAATAGGATTGCTTAAATATATGAATTCTGGTGGTCTTCTTACTATGAGCTTAGAGCGGGACCTTCTTGACACTGAGCCCATGAAGGAACTTAGCAGCAAGCGTCCTCTGGTGTGCTCCGAGGTTAATGGGCAGCCAGTTCTCTTAAAGGGCTATTCCGTGGATGTTGACACAGAAGGCAGGGTGATTCAGAGAGCAGCCTCTTACCATAGAGCTTGTGGATATGCTAAAGAAGAGTCTGGGTTACTGCCATTAATATTCTTGTTTTTGTGTAAGTCTGATCCTGTTGCCTATCTGATGGTCCCATATTATCCTAAGGCAAACCTGAGTGCAGTTCAAGCCAGTATGCCTTTAACTTCAGAAGAAGCTTTAAAAGTCATGAAAGGTGTTGCCC

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Gene Information

mouse ... STK11(20869), Stk11(20869)

Gene Information

mouse ... SDC1(20969), Sdc1(20969)

Gene Information

mouse ... SIPA1(20469), Sipa1(20469)

Gene Information

mouse ... STK31(77485), Stk31(77485)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Classe di stoccaggio

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Fanny Dupuy et al.
Cancer & metabolism, 1(1), 18-18 (2013-11-28)
Germline and somatic mutations in STK11, the gene encoding the serine/threonine kinase LKB1, are strongly associated with tumorigenesis. While loss of LKB1 expression has been linked to breast cancer, the mechanistic role of LKB1 in regulating breast cancer development, metastasis
Juan Li et al.
Journal of experimental & clinical cancer research : CR, 33, 70-70 (2014-09-03)
LKB1, also known as STK11, is a master kinase that serves as an energy metabolic sensor and is involved in cell polarity regulation. Recent studies have indicated that LKB1 is related to breast tumorigenesis and breast cancer progression. However, little
Ngai Na Co et al.
Cancer, 120(22), 3457-3468 (2014-07-22)
Liver kinase B1 (LKB1) is a serine/threonine kinase that functions as a tumor suppressor and regulates cell polarity, proliferation, and metabolism. Mutations in LKB1 are associated with Peutz-Jeghers syndrome as well as sporadic cervical and lung cancers. Although LKB1-null mice
Shabnam Pooya et al.
Nature communications, 5, 4993-4993 (2014-09-27)
A prerequisite to myelination of peripheral axons by Schwann cells (SCs) is SC differentiation, and recent evidence indicates that reprogramming from a glycolytic to oxidative metabolism occurs during cellular differentiation. Whether this reprogramming is essential for SC differentiation, and the
Kaisheng Mao et al.
Lung cancer (Amsterdam, Netherlands), 88(2), 131-138 (2015-03-15)
The tumor suppressor LKB1 has recently been shown to be involved in the regulation of microtubule dynamics, thus cancer cells with inactivated LKB1 may have developed a means to overcome dysregulated microtubule functions, making them intrinsically resistant to microtubule targeting
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