P9879

Procain -hydrochlorid

≥97% (HPLC), powder, Na⁺ channel blocker

• Synonym(e): 4-Aminobenzoesäure-2-diethylaminoethylester -hydrochlorid, p-Aminobenzoesäure-diethylaminoethylester -hydrochlorid, Novocain -hydrochlorid
• Lineare Formel: H₂NC₆H₄CO₂CH₂CH₂N(C₂H₅)₂·HCl
• CAS-Nummer: 51-05-8
• Molekulargewicht: 272.77
• NACRES: NA.77
• PubChem Substance ID: 24278665
• UNSPSC Code: 12352200
• EC Number: 200-077-2
• MDL number: MFCD00013000
• Beilstein/REAXYS Number: 3917802

Eigenschaften

• Produktname: Procain -hydrochlorid, ≥97%
• InChI key: HCBIBCJNVBAKAB-UHFFFAOYSA-N
• InChI: 1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H
• SMILES string: Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1
• assay: ≥97%
• form: powder
• mp: 155-156 °C (lit.)
• originator: Celgene
• Quality Level: 200
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Beschreibung

Application

Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length.[1] It has also been used as an inducer in M9 media for induction assay.[2]

Biochem/physiol Actions

Procaine is a Na⁺ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine.[3] It is also useful as a painkiller to treat pain, associated with joints and tendons.[4]

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Celgene. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H317
• pcodes: P261 - P264 - P270 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Skin Sens. 1
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges