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Merck

N9125

N-(1-Naphthyl)ethylenediamine dihydrochloride

≥98%

Synonym(s):

2-(1-Naphthylamino)ethylamine dihydrochloride

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About This Item

Linear Formula:
C10H7NHCH2CH2NH2 · 2HCl
CAS Number:
1465-25-4
Molecular Weight:
259.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
57654471
EC Number:
215-981-2
Beilstein/REAXYS Number:
3707471
MDL number:
MFCD00012556

Key Documents

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Product Name

N-(1-Naphthyl)ethylenediamine dihydrochloride, ≥98%

assay

≥98%

form

powder

InChI key

MZNYWPRCVDMOJG-UHFFFAOYSA-N

InChI

1S/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H

SMILES string

Cl.Cl.NCCNc1cccc2ccccc12

mp

194-198 °C (dec.) (lit.)

Quality Level

200

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Application

N-(1-Naphthyl)ethylenediamine dihydrochloride can be used as a reactant to synthesize:      
  • N


  • -(1-naphthyl)ethylenediamine-substituted cylotriphosphazene derivatives as potential antimicrobial agents.    
  • Fluorescent chemosensor compound with a naphthyl group as fluorophore and cyclen as metal ion chelator for the detection of Zn(II) in an aqueous solution.    
  • (N-1-Naphthyl-ethylenediamine)- dichloroplatinum(II) fluorescence complex (λmax = 405 nm).

General description

N-(1-Naphthyl)ethylenediamine dihydrochloride is an organic compound with a conjugated ring structure that serves as a strong electron donor in charge transfer complexes. Its free base, also known as Bratton-Marshall reagent, is widely used in diazotization coupling reactions for detecting nitrites and nitrates.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000520858
0000520858
MKCZ5678
0000510143
0000510143

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Raquel Morais de Paiva Daibert et al.
PloS one, 15(11), e0241861-e0241861 (2020-11-07)
Macrophages are classified upon activation as classical activated M1 and M2 anti-inflammatory regulatory populations. This macrophage polarization is well characterized in humans and mice, but M1/M2 profile in cattle has been far less explored. Bos primigenius taurus (taurine) and Bos
Improved dye procedure for determining urea concentration by using o-phthalaldehyde and naphthylethylenediamine.
N T Lequang et al.
Clinical chemistry, 33(1), 192-192 (1987-01-01)
P K Laikind et al.
Analytical biochemistry, 156(1), 81-90 (1986-07-01)
The Bratton-Marshall reaction can be used to identify patients with adenylosuccinate lyase deficiency. These patients excrete in their urine the dephosphorylated derivative of the de novo purine synthesis intermediate 5'-phosphoribosyl-4-(N-succinylcarboxamide)-5-aminoimidazole (SAICAR). The test described here depends on a coupling reaction
J A Cook et al.
Analytical biochemistry, 238(2), 150-158 (1996-07-01)
S-nitrosothiols have been shown to affect a number of physiological functions. Several techniques have been used to detect these species in biological systems, primarily by methods utilizing chemiluminescence. Since the apparatus required for measurement of chemiluminescence are not readily available
Basavaraj Hiremath et al.
Acta pharmaceutica (Zagreb, Croatia), 58(3), 275-285 (2008-12-24)
Two spectrophotometric methods for the determination of ceftazidime (CFZM) in either pure form or in its pharmaceutical formulations are described. The first method is based on the reaction of 3-methylbenzothiazolin-2-one hydrazone (MBTH) with ceftazidime in the presence of ferric chloride
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