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Merck

860345C

Avanti

14:0 PC-d54

Avanti Research™ - A Croda Brand

Synonym(s):

DMPC-D54

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About This Item

Empirical Formula (Hill Notation):
C36H18NO8PD54
CAS Number:
78415-49-3
Molecular Weight:
732.27
MDL number:
MFCD00151586
UNSPSC Code:
51191904
NACRES:
NA.25

Key Documents

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Product Name

14:0 PC-d54, 1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine, chloroform

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H

InChI

1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m1/s1/i1D3,2D3,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D2,21D2,22D2,23D2,24D2,25D2,26D2,27D2,28D2,29D2

InChI key

CITHEXJVPOWHKC-RPLUSTTMSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (860345C-10mg)
pkg of 1 × 4 mL (860345C-100mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860345C

concentration

10 mg/mL (860345C-10mg)
25 mg/mL (860345C-100mg)

shipped in

dry ice

storage temp.

−20°C

Application

14:0 PC-d54 is suitable to reconstitute [ILV-13CH3, U-15N, 2H] labeled EmrE in n-dodecyl-β-D-maltopyranoside (DDM) back-exchanged to 1H at the amide positions during nuclear magnetic resonance (NMR) sample preparation. It is also suitable for the preparation of phospholipid liposomes.

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Packaging

5 mL Clear Glass Sealed Ampule (860345C-100mg)
5 mL Clear Glass Sealed Ampule (860345C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

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Jess Li et al.
The Journal of biological chemistry, 295(9), 2664-2675 (2020-01-25)
Engineering and bioconjugation of proteins is a critically valuable tool that can facilitate a wide range of biophysical and structural studies. The ability to orthogonally tag or label a domain within a multidomain protein may be complicated by undesirable side
Protonation of a glutamate residue modulates the dynamics of the drug transporter EmrE
Gayen A, et al.
Nature chemical biology, 12(3), 141-141 (2016)
Fusion of Legionella pneumophila outer membrane vesicles with eukaryotic membrane systems is a mechanism to deliver pathogen factors to host cell membranes
Jager J, et al.
Cellular Microbiology, 17(5), 607-620 (2015)
Alessio Ausili et al.
Langmuir : the ACS journal of surfaces and colloids, 36(4), 1062-1073 (2020-01-14)
Vitamin K1 and vitamin K2 play very important biological roles as members of chains of electron transport as antioxidants in membranes and as cofactors for the posttranslational modification of proteins that participate in a number of physiological functions such as
Stephen C L Hall et al.
Journal of colloid and interface science, 574, 272-284 (2020-04-25)
Over recent years, there has been a rapid development of membrane-mimetic systems to encapsulate and stabilize planar segments of phospholipid bilayers in solution. One such system has been the use of amphipathic copolymers to solubilize lipid bilayers into nanodiscs. The
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Articles

Critical Micelle Concentrations (CMCs) - Avanti Research™ Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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