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Merck

14-251-M

p38α/SAPK2a Protein, active, 10 µg

Active, N-terminal GST tagged, recombinant, full length p38α/SAPK2a, for use in Kinase Assays.

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14-251

HUF 194,000.00

14-251M

HUF 1,250,000.00

HUF 194,000.00


Estimated to ship onJanuary 08, 2026Details


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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

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biological source

human

Quality Level

recombinant

expressed in E. coli

mol wt

Mw 67.7 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

UniProt accession no.

Gene Information

human ... MAPK14(1432)

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This Item
14-253-M14-246-M14-249-M
recombinant

expressed in E. coli

recombinant

-

recombinant

expressed in E. coli

recombinant

expressed in E. coli

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

biological source

human

biological source

human

biological source

human

biological source

human

mol wt

Mw 67.7 kDa

mol wt

Mw 71 kDa

mol wt

Mw 69 kDa

mol wt

Mw 71 kDa

Gene Information

human ... MAPK14(1432)

Gene Information

-

Gene Information

human ... PEBP1(5037)

Gene Information

-

UniProt accession no.

Q16539

UniProt accession no.

Q15759

UniProt accession no.

P30086

UniProt accession no.

O15264

General description

N-terminal GST tagged, recombinant, full length p38α/SAPK2a
Product Source: expressed in E. coli

Biochem/physiol Actions

Protein Target: p38α/SAPK2a
Target Sub-Family: CMGC

Packaging

Also available in 250μg size (2x125μg) - Call for pricing and availability. Please reference catalog number 14-251M when ordering the 250μg size.

Physical form

Glutathione-agarose

Preparation Note

6 months at -20°C

Analysis Note

Routinely evaluated by phosphorylation of MBP

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Y N Doza et al.
FEBS letters, 364(2), 223-228 (1995-05-08)
A MAP kinase homologue, termed the reactivating kinase (RK), lies in a signalling pathway which mediates cellular responses to stress. Here we demonstrate that the stress-induced activation of the RK in human KB cells is accompanied by the phosphorylation of
A Cuenda et al.
FEBS letters, 364(2), 229-233 (1995-05-08)
A class of pyridinyl imidazoles inhibit the MAP kinase homologue, termed here reactivating kinase (RK) [Lee et al. (1994) Nature 372, 739-746]. We now show that one of these compounds (SB 203580) inhibits RK in vitro (IC50 = 0.6 microM)
A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway.
Ben-Levy, R, et al.
The Embo Journal, 13, 3302-3311 (1994)

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