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Merck

40234

N,N-Dimethyldodecylamine N-oxide

BioXtra, ≥99.0% (NT)

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

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About This Item

Linear Formula:
CH3(CH2)11N(O)(CH3)2
CAS Number:
1643-20-5
Molecular Weight:
229.40
UNSPSC Code:
12161902
NACRES:
NA.26
PubChem Substance ID:
57649946
EC Number:
216-700-6
Beilstein/REAXYS Number:
1769927
MDL number:
MFCD00002049

Key Documents

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Product Name

N,N-Dimethyldodecylamine N-oxide, BioXtra, ≥99.0% (NT)

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

SMILES string

CCCCCCCCCCCC[N+](C)(C)[O-]

description

non-ionic
sulfate (ICP): ≤ 50 mg/kg

product line

BioXtra

assay

≥99.0% (NT)

form

powder

mol wt

229.40 g/mol

technique(s)

protein quantification: suitable

impurities

≤0.03% peroxides (as H2O2)

CMC

1-2 mM

mp

132-133 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤100 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

storage temp.

2-8°C

Quality Level

200

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Show Differences

1 of 4

This Item
401034023640166
N,N-Dimethyldodecylamine N-oxide BioXtra, ≥99.0% (NT)

Sigma-Aldrich

40234

N,N-Dimethyldodecylamine N-oxide

N,N-Dimethyldecylamine N-oxide ≥99.0% (NT)

Sigma-Aldrich

40103

N,N-Dimethyldecylamine N-oxide

N,N-Dimethyldodecylamine N-oxide solution ~30% in H2O

Sigma-Aldrich

40236

N,N-Dimethyldodecylamine N-oxide solution

N,N-Dimethyltetradecylamine N-oxide ≥98.0% (NT)

Sigma-Aldrich

40166

N,N-Dimethyltetradecylamine N-oxide

form

powder

form

powder

form

liquid

form

powder

assay

≥99.0% (NT)

assay

≥99.0% (NT)

assay

-

assay

≥98.0% (NT)

technique(s)

protein quantification: suitable

technique(s)

-

technique(s)

protein quantification: suitable

technique(s)

protein purification: suitable, protein quantification: suitable

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

cation traces

Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤100 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Zn: ≤5 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Na: ≤50 mg/kg, Cr: ≤5 mg/kg, Pb: ≤5 mg/kg, Mg: ≤5 mg/kg

cation traces

Ca: ≤500 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤50 mg/kg, Mn: ≤5 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

cation traces

-

cation traces

-

description

non-ionic

description

non-ionic

description

non-ionic

description

-

Application

N,N-Dimethyldodecylamine N-oxide has been used in the cell lysis and resuspension of cell pellets for western blot analysis.

General description

N,N-Dimethyldodecylamine N-oxide is a non-denaturing zwitterionic surfactant with a critical micelle concentration (CMC) of approximately 1 mM. It is used to solubilize proteins and to study the conformation and molecular interactions of macromolecules.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9772
0000331372
BCCK7525
BCCM2621
0000331372

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Vasyl Bondarenko et al.
Biochimica et biophysica acta, 1818(5), 1261-1268 (2012-03-01)
The α4β2 nicotinic acetylcholine receptor (nAChR) is the predominant heteromeric subtype of nAChRs in the brain, which has been implicated in numerous neurological conditions. The structural information specifically for the α4β2 and other neuronal nAChRs is presently limited. In this
Xiaoyi Deng et al.
Journal of medicinal chemistry, 57(12), 5381-5394 (2014-05-08)
Malaria is one of the most serious global infectious diseases. The pyrimidine biosynthetic enzyme Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) is an important target for antimalarial chemotherapy. We describe a detailed analysis of protein-ligand interactions between DHODH and a triazolopyrimidine-based inhibitor
Achim Stocker et al.
Journal of structural biology, 152(2), 140-145 (2005-10-18)
Recently, we reported the cloning of the atp operon encoding for the F(1)F(0)-ATP synthase from the extremely thermoalkaliphilic bacterium Bacillus sp. strain TA2.A1. In this study, the genes encoding the F(1) moiety of the enzyme complex were cloned from the
Eugenio Daviso et al.
Journal of the American Chemical Society, 133(42), 16754-16757 (2011-10-04)
Several techniques rely on electron-nuclear interactions to boost the polarization of nuclear spins in the solid phase. Averaging out of anisotropic interactions as a result of molecular tumbling strongly reduces the applicability of such hyperpolarization approaches in liquids. Here we
Stefanie Keis et al.
Journal of bacteriology, 188(11), 3796-3804 (2006-05-19)
The F(1)F(o)-ATP synthases of alkaliphilic bacteria exhibit latent ATPase activity, and for the thermoalkaliphile Bacillus sp. strain TA2.A1, this activity is intrinsic to the F(1) moiety. To study the mechanism of ATPase inhibition, we developed a heterologous expression system in
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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