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Merck

B4679

BIS-TRIS propane

BioPerformance Certified, suitable for cell culture, ≥99.0%

Synonym(s):

1,3-Bis[tris(hydroxymethyl)methylamino]propane

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HUF 43,600.00

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HUF 123,000.00

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HUF 413,000.00

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About This Item

Linear Formula:
CH2[CH2NHC(CH2OH)3]2
CAS Number:
64431-96-5
Molecular Weight:
282.33
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
24891799
EC Number:
264-899-3
Beilstein/REAXYS Number:
1786109
MDL number:
MFCD00004689

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Product Name

BIS-TRIS propane, BioPerformance Certified, suitable for cell culture, ≥99.0%

InChI key

HHKZCCWKTZRCCL-UHFFFAOYSA-N

InChI

1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2

SMILES string

OCC(CO)(CO)NCCCNC(CO)(CO)CO

grade

BioPerformance Certified

assay

≥99.0%

form

crystals

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and bioburden, tested

useful pH range

6.3-9.5

pKa (25 °C)

(1) 6.8, (2) 9.0

mp

164-165 °C (lit.)

application(s)

diagnostic assay manufacturing

foreign activity

DNAse (exonuclease), NICKase (endonuclease), RNAse, and protease, none detected

Quality Level

400

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Show Differences

1 of 4

This Item
B9410B6755RDD014
BIS-TRIS propane BioPerformance Certified, suitable for cell culture, ≥99.0%

Sigma-Aldrich

B4679

BIS-TRIS propane

BIS-TRIS propane BioXtra, ≥99.0% (titration)

Sigma-Aldrich

B9410

BIS-TRIS propane

BIS-TRIS propane ≥99.0% (titration)

Sigma-Aldrich

B6755

BIS-TRIS propane

BIS-TRIS propane anhydrous, free-flowing, Redi-Dri™, ≥99.0%

Sigma-Aldrich

RDD014

BIS-TRIS propane

grade

BioPerformance Certified

grade

-

grade

-

grade

anhydrous

assay

≥99.0%

assay

≥99.0% (titration)

assay

≥99.0% (titration)

assay

≥99.0%

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable

technique(s)

-

Quality Level

400

Quality Level

400

Quality Level

400

Quality Level

100

form

crystals

form

powder

form

powder

form

powder

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing
general analytical
life science and biopharma

application(s)

-

Application

  • Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor.: BIS-TRIS propane is used in the development of nanowire field-effect transistors for detecting GC-rich RNA sequences. The study demonstrates the buffer′s role in enhancing the specificity and sensitivity of these biosensors (Chou et al., 2019).

  • Elimination of ghost peaks by optimization of anion exchange chromatography method for determination of gamma-carboxyglutamic acid (Gla)-domainless impurity in recombinant activated clotting factor VII drug products.: BIS-TRIS propane is employed in optimizing chromatography methods to eliminate ghost peaks during the analysis of pharmaceutical impurities. The buffer′s effectiveness ensures accurate and reliable detection of impurities in drug formulations (Tahmasbi et al., 2019).

Other Notes

Easily compare specifications for BIS-TRIS propane products with the BIS-TRIS propane specification table.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000506111
0000506111
0000471467
0000471468
0000471467

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R Tóth-Boconádi et al.
Biophysical journal, 78(6), 3170-3177 (2000-05-29)
Buffers change the electric signals of light-excited bacteriorhodopsin molecules in purple membrane if their concentration and the pH of the low-salt solution are properly selected. "Positive" buffers produce a positive component, and "negative" buffers a negative component in addition to
R Coronado et al.
The Journal of general physiology, 79(4), 529-547 (1982-04-01)
A collection of organic cations has been used to probe the gross structural features of the ionic diffusion pathway in a K+-selective channel from sarcoplasmic reticulum (SR). Channels were incorporated into planar phospholipid bilayer membranes, and single-channel currents were measured
Joseph S Brunzelle et al.
Archives of biochemistry and biophysics, 474(1), 157-166 (2008-04-01)
The three-dimensional structure of the catalytically efficient beta-xylosidase from Selenomonas ruminantium in complex with competitive inhibitor 1,3-bis[tris(hydroxymethyl)methylamino]propane (BTP) was determined by using X-ray crystallography (1.3A resolution). Most H bonds between inhibitor and protein occur within subsite -1, including one between
P Gómez-Tagle et al.
Inorganic chemistry, 40(15), 3786-3796 (2001-07-10)
Potentiometric titrations of the mixtures of lanthanide(III) perchlorates and bis-Tris propane (BTP) reveal formation of dinuclear hydroxo complexes M2(BTP)2(OH)n(6-n), where M = La(III), Pr(III), Nd(III), Eu(III), Gd(III), and Dy(III) and n = 2, 4, 5, or 6, in the pH
Sami J O Varjo et al.
Journal of chromatography. A, 1081(1), 92-98 (2005-07-15)
Greater stability of liposome coatings and improved resolution of model steroids in capillary electrochromatography (CEC) were sought by adding small diamines (ethylenediamine, diaminopropane, bis-tris-propane, or N-(2-hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid, HEPES)) to the liposome solution before coating of fused silica capillaries. The phospholipid
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