Skip to Content
Merck

D5946

PD 150606

≥97% (HPLC)

Synonym(s):

(2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid, 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

Select a Size

5 MG

HUF 46,800.00

25 MG

HUF 186,000.00

HUF 46,800.00

Please contact Customer Service for Availability
Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C9H7IO2S
CAS Number:
179528-45-1
Molecular Weight:
306.12
MDL number:
MFCD00949076
UNSPSC Code:
12352200
PubChem Substance ID:
329798817
NACRES:
NA.77

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

100

Assay

≥97% (HPLC)

form

powder

storage condition

protect from light

color

yellowish

solubility

DMSO: >20 mg/mL

storage temp.

−20°C

SMILES string

OC(=O)\C(S)=C\c1ccc(I)cc1

InChI

1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-

InChI key

DJCVSFWGKYHMKH-YVMONPNESA-N

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
513022SML1950U6883
PD 150606 ≥97% (HPLC)

Sigma-Aldrich

D5946

PD 150606

PD 150606 A cell-permeable, non-competitive, selective non-peptide calpain inhibitor [Ki = 210 nM for calpain-1 and 370 nM for calpain-2.

Sigma-Aldrich

513022

PD 150606

UVI3003 ≥98% (HPLC)

Sigma-Aldrich

SML1950

UVI3003

cis-Urocanic acid ≥98% (HPLC), solid (fluffy)

Sigma-Aldrich

U6883

cis-Urocanic acid

assay

≥97% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

solid

form

powder

form

solid (fluffy)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

protect from light

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

protect from light

solubility

DMSO: >20 mg/mL

solubility

DMSO: 100 mg/mL, methanol: 25 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

H2O: >10 mg/mL

Biochem/physiol Actions

PD 150606 is a selective; cell-permeable; non-peptide; uncompetitive calpain inhibitor.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H301,H315,H317,H318,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000054896
105M4605V
012M4601V
040M4622

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Shuchen Hsieh et al.
Journal of nanoscience and nanotechnology, 9(5), 2894-2901 (2009-05-21)
Aminopropylsilatrane (AP-silatrane) was investigated as an adhesive layer for anchoring Au nanoparticles on silicon substrates. We compared the preparation procedure and film quality of the AP-silatrane films to those of 3-aminopropyltriethoxysilane (APTES), which is commonly used for nanoparticle attachment on
Seon Goo Kim et al.
Journal of cellular biochemistry, 119(7), 5620-5631 (2018-02-02)
Resistance to anoikis and growth in anchorage-independent conditions are hallmarks of highly metastatic cancer cells. Anoikis is a type of apoptosis induced by inadequate cell/extracellular matrix (ECM) attachment and an attractive anti-cancer therapeutic strategy in cancer chemotherapeutic field. Therefore, the
Debora Gentile et al.
Biochemical and biophysical research communications, 533(4), 764-769 (2020-09-30)
The molecular target and mechanism by which d-limonene induces LC3 lipidation and autophagosome formation remain elusive. Here, we report that this monoterpene rapidly enhances Ca2+ levels in SH-SY5Y cells; yet this effect does not lead to calpain- or caspase-mediated proteolysis
Rosalie Heilig et al.
Life science alliance, 3(6) (2020-04-30)
Caspase-1 drives a lytic inflammatory cell death named pyroptosis by cleaving the pore-forming cell death executor gasdermin-D (GSDMD). Gsdmd deficiency, however, only delays cell lysis, indicating that caspase-1 controls alternative cell death pathways. Here, we show that in the absence
Hong Wang et al.
Journal of inorganic biochemistry, 172, 16-22 (2017-04-19)
Calcium, as a ubiquitous second messenger, governs a large array of cellular processes and is necessary for cell survival. More recently, it was observed that the cytosolic Ca
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service