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Merck

T8941

L-Tryptophan

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Synonym(s):

(S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid

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10 MG

HUF 12,400.00

25 G

HUF 26,400.00

100 G

HUF 82,500.00

1 KG

HUF 500,000.00

HUF 12,400.00


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About This Item

Empirical Formula (Hill Notation):
C11H12N2O2
CAS Number:
Molecular Weight:
204.23
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-795-6
MDL number:
Beilstein/REAXYS Number:
86197

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Product Name

L-Tryptophan, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

InChI key

QIVBCDIJIAJPQS-VIFPVBQESA-N

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

SMILES string

N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

biological source

non-animal source

agency

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

product line

BioXtra

assay

99.0-101.0%

form

powder

quality

meets EP, JP, USP testing specifications

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to yellow

mp

280-285 °C (dec.) (lit.)

solubility

1 M HCl: 10 mg/mL

application(s)

pharmaceutical (small molecule)

Quality Level

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1 of 4

This Item
1700501PHR1176T2610000
form

powder

form

-

form

-

form

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

assay

99.0-101.0%

assay

-

assay

-

assay

-

product line

BioXtra

product line

-

product line

-

product line

-

Quality Level

300

Quality Level

-

Quality Level

300

Quality Level

-

solubility

1 M HCl: 10 mg/mL

solubility

-

solubility

-

solubility

-

Application

L-Tryptophan has been used in PreC media preparation and in cell culture.[1][2]

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that is associated with growth, reproduction, maintenance and immunity.[3] Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.[4]

Other Notes

Amino acid precursor of serotonin and melatonin

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Danielle N A Lesperance et al.
Applied and environmental microbiology, 87(1) (2020-10-18)
Drosophila melanogaster gut microbes play important roles in host nutritional physiology. However, these associations are often indirect, and studies typically are in the context of specialized nutritional conditions, making it difficult to discern how microbiome-mediated impacts translate to physiologically relevant
Amino acids: metabolism, functions, and nutrition
Amino Acids (2009)
Nutrient supplements boost yeast
transformation efficiency
Sheng-ChunYu
Scientific Reports (2016)
Preparation of Purified Gram-positive Bacterial Cell Wall and Detection in Placenta and Fetal Tissues
Beth Mann
Bio-protocol, 6(23) (2016)
Effects of tryptophan loading on human cognition, mood, and sleep
B.Y. Silber and J.A.J. Schmitt
Neuroscience and Biobehavioral Reviews, 34(3), 387-407 (2010)

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. Which is the presnetation of the 10 mg Tryptophan? polyethilen or glass bottles

    1 answer
    1. This product is supplied as a crystalline powder. The 10 mg size is packaged in a 2 mL amber glass bottle.

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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