[Estimating ability of dihydroquercetin to inhibit oxidation of fibrinogen by ozone].

[Estimating ability of dihydroquercetin to inhibit oxidation of fibrinogen by ozone].

Eksperimental'naia i klinicheskaia farmakologiia (2013-06-19)

V S Rogovskiĭ, M A Rozenfel'd, S D Razumovskiĭ, A I Matiushin, N L Shimanovskiĭ, B V Leonova, M L Konstantinova

ABSTRACT

The ability of dihydroquercetin to inhibit the oxidation of fibrinogen has been evaluated. It is established that dihydroquercetin inhibits oxidation of fibrinogen by ozone, thus preventing oxidative modification of fibrinogen and preserving its functional activity.

MATERIALS

Product Number

Brand

Product Description

78666

Supelco

Taxifolin, analytical standard

F6755

Sigma-Aldrich

Fibrinogen from rat plasma, 60-80% protein (≥60% of protein is clottable)

F4883

Sigma-Aldrich

Fibrinogen from human plasma, 35-65% protein (≥90% of protein is clottable).

F3879

Sigma-Aldrich

Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable)

F8630

Sigma-Aldrich

Fibrinogen from bovine plasma, Type I-S, 65-85% protein (≥75% of protein is clottable)