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Merck

B950-05

Bovine Renal Artery Smooth Muscle Cells: BRASMC (Cryovial)

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NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
bovine renal artery (normal, tunica intima and media)
Growth mode:
Adherent
Morphology:
smooth muscle
Relevant disease(s):
renal disease; cardiovascular diseases
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biological source

bovine renal artery (normal, tunica intima and media)

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 60

morphology

smooth muscle

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

renal disease; cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

General description

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Bovine Renal Artery Smooth Muscle Cells (BRASMC) are derived from tunica intima and tunica media of normal bovine renal arteries. They are cryopreserved at second passage and can be cultured and propagated at least 12 population doublings. Studies show cyclosporine-induced renal artery smooth muscle contraction is associated with increases in the phosphorylation of specific contractile regulatory proteins1. The renal artery smooth muscle is uniquely refractory to angiotensin stimulation and may be protective in the role of the kidney in regulating blood pressure through the renin-angiotensin system2.

Beall, A. et al, Biochem Biophys Acta., 1449(1):41-9 (1999)
Whitney, E.G. et al, J. Surg. Res. 61(2):307-10 (1996)

Products are for research use only. They are not intended for human, animal, or diagnostic application.
Animal tissues were USDA inspected.

Application

blood flow to kidneys

Biochem/physiol Actions

Artery

Preparation Note

  • 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 12 doublings
Please refer to the BRASMC Culture Protocol.

Other Notes

Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO


保管分類

11 - Combustible Solids

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WGK 3

匕火点 (F)

Not applicable

匕火点°C

Not applicable



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