F0806

第IX因子 ヒト

aqueous glycerol solution, ≥145 units/mg protein

• 別名: クリスマス因子, 血漿トロンボプラスチン成分
• CAS番号: 9001-28-9
• UNSPSC Code: 12352202
• NACRES: NA.61
• MDL number: MFCD00163303
• Form: aqueous glycerol solution
• Biological source: human
• Mol wt: 55 kDa

特性

• biological source: human
• Quality Segment: 200
• form: aqueous glycerol solution
• specific activity: ≥145 units/mg protein
• mol wt: 55 kDa
• technique(s): ligand binding assay: suitable
• UniProt accession no.: P00740
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... F9(2158)

詳細

General description

第IX因子は55 kDaの単鎖、ビタミンK依存性、血漿中のチモーゲンで、内因性および外因性の血液凝固系において重要な役割を果たしています。

Application

Factor IX is plasma zymogen key to blood coagulation systems. It has been used in studies of portal vein thrombosis (PVT) in hepatocellular carcinoma (HCC). It has been found that abnormalities in factor IX contribute to PVT in HCC patients. Additionally, it has been used in studies of changes in the coagulation system in patients with inflammatory bowel disease (IBD).

Physical form

50%(v/v)グリセロール含有水溶液。

Other Notes

1ユニットは、pH 7.4、37°Cの正常ヒト血漿1.0 mL中の第IX因子活性と等しい酵素活性です。

この因子の機能についてはCoagulation Cascadeをご参照ください。

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

安全性情報

• 保管分類: 10 - Combustible liquids
• 一体何が起きているの？: WGK 1
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable
• PPE（個人用保護具）: Eyeshields, Gloves, type N95 (US)