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P1495

抗ホスファチジルセリンレセプターウサギ宿主抗体

Name: 抗ホスファチジルセリンレセプター ウサギ宿主抗体
Brand: SIGMA
Price: 87900 JPY

1-1.5 mg/mL, affinity isolated antibody, buffered aqueous solution

別名:

抗PSR抗体

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あなたへ/カタログ番号	在庫状況	単価
200 μL	カートの在庫状況を確認する	￥87,900

この商品について

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD04040521

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, IP, WB

Citations:

￥87,900

カートの在庫状況を確認する

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特性

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 50-70 kDa

species reactivity

mouse, human

concentration

1-1.5 mg/mL

technique(s)

immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1:1,000 using whole extracts of human HeLa or A549 cells, western blot: 1:500 using whole extracts of mouse NIH3T3 cells

UniProt accession no.

Q6NYC1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... JMJD6(23210)
mouse ... Jmjd6(107817)

詳細

General description

Phosphatidylserine Receptor (PSR) is an evolutionarily conserved glycoprotein that is widely expressed in cells and tissues. It is very susceptible to cleavage by protease or elastase. PSR engagement plays an important role in macro-pinocytosis and uptake of tethered apoptotic cells. Cooperation with other receptors and their ligands may also be needed for ingestion of apoptotic cells. PSR is involved in suppression of inflammatory and immune responses.

Phosphatidylserine receptor belongs to the group of Jumonji domain containing protein 6 (JMJD6). It is known to be localized to the phagocytes. PSR is an evolutionarily conserved glycoprotein that is widely expressed in cells and tissues.

Immunogen

synthetic peptide corresponding to amino acid residues 363-381 of the human phosphatidylserine receptor conjugated to maleimide-activated KLH. The corresponding sequence in mouse differs by one amino acid.

Application

Anti-Phosphatidylserine Receptor antibody is sutiable for use in immunoprecipitation and immunoblotting (~50-70 kDa) applications.

Biochem/physiol Actions

Anti-Phosphatidylserine Receptor (PSR) recognizes human and mouse phosphatidylserine receptor (PSR). Detection of the phosphatidylserine receptor by immunoblotting is specifically inhibited by the immunizing peptide, a synthetic peptide corresponding to amino acid residues 363-381 of the human phosphatidylserine receptor, conjugated to maleimide-activated KLH as immunogen.

Phosphatidylserine receptor (PSR) is very susceptible to cleavage by protease or elastase. PSR engagement plays an important role in macro-pinocytosis and uptake of tethered apoptotic cells. Cooperation with other receptors and their ligands may also be needed for ingestion of apoptotic cells. PSR is involved in suppression of inflammatory and immune responses.

Physical form

0.01M PBS溶液 (pH 7.4, 1% BSA, 15mMアジ化ナトリウム含有)。

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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当該品目	P0497	R8656	R3653
Sigma-Aldrich P1495 抗ホスファチジルセリンレセプターウサギ宿主抗体	Sigma-Aldrich P0497 抗PMP70抗体ウサギ宿主抗体	Sigma-Aldrich R8656 Anti-Peroxiredoxin 2 (C-terminal) antibody produced in rabbit	Sigma-Aldrich R3653 抗ラディキシン抗体ウサギ宿主抗体
description 1-1.5 mg/mL, affinity isolated antibody, buffered aqueous solution	description affinity isolated antibody, buffered aqueous solution	description ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution	description affinity isolated antibody, buffered aqueous solution
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
technique(s) immunoprecipitation (IP): suitable, western blot: 1:1,000 using whole extracts of human HeLa or A549 cells, microarray: suitable, western blot: 1:500 using whole extracts of mouse NIH3T3 cells	technique(s) immunoprecipitation (IP): 1-2 μg using RIPA extract (0.5 mg) from human HepG2 cells, indirect immunofluorescence: 4-8 μg/mL using mouse NIH3T3 cells, western blot (chemiluminescent): 0.5-1 μg/mL using whole extracts of rat PC12 cells or rat kidney extract or rat liver extract	technique(s) immunoprecipitation (IP): 2.0-5.0 μg using lysate of mouse 3T3 cells, western blot: 0.5-1.0 using whole extract of human HeLa cells, western blot: 1-2 μg/mL using whole extract of rat NRK cells	technique(s) immunoprecipitation (IP): 10-20 μg using RIPA extract (250 μg) of rat liver, indirect immunofluorescence: 10-20 μg/mL using cultured human HeLa cells, western blot: 1-2 μg/mL using whole extract of cultured HeLa cells, western blot: 1-2 μg/mL using whole extract of cultured mouse NIH3T3 cells

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保管分類

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c