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Merck

BPGM

2,3-bisphosphoglycerate mutase

동의어:
DPGM
:
UniProtKB ID:
Clone ID:
  • Human(669) Summary: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]
  • Mouse(12183) 2,3-bisphosphoglycerate mutase
  • Rat(296973) 2,3-bisphosphoglycerate mutase
  • Zebrafish(436903) 2,3-bisphosphoglycerate mutase
  • domestic cat(101095644) 2,3-bisphosphoglycerate mutase
  • dog(482704) 2,3-bisphosphoglycerate mutase
  • domestic guinea pig(100722842) 2,3-bisphosphoglycerate mutase
  • Domestic Rabbit(100009096) 2,3-bisphosphoglycerate mutase
  • sheep(101121089) 2,3-bisphosphoglycerate mutase
  • cow(533785) 2,3-bisphosphoglycerate mutase
  • naked mole-rat(101706859) 2,3-bisphosphoglycerate mutase
  • chicken(418172) 2,3-bisphosphoglycerate mutase

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-BPGM antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human BPGM,
human
MISSION® esiRNA, targeting mouse Bpgm,
mouse