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Merck

762342

Tris(3-hydroxypropyltriazolylmethyl)amine

95%, solid

Tris(3-hydroxypropyltriazolylmethyl)amine
1 of 1 reviewers received a sample product or took part in a promotion

Sinónimos:

3,3′,3′′-(4,4′,4′′-(Nitrilotris(methylene))tris(1H-1,2,3-triazole-4,1-diyl))tris(propan-1-ol), THPTA

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Fórmula empírica (notación de Hill):
C18H30N10O3
Número CAS:
760952-88-3
Peso molecular:
434.50
UNSPSC Code:
12352300
PubChem Substance ID:
329766966
NACRES:
NA.22
MDL number:
MFCD27665386

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Nombre del producto

Tris(3-hydroxypropyltriazolylmethyl)amine, 95%

SMILES string

OCCCN1N=NC(CN(CC2=CN(CCCO)N=N2)CC3=CN(CCCO)N=N3)=C1

InChI

1S/C18H30N10O3/c29-7-1-4-26-13-16(19-22-26)10-25(11-17-14-27(23-20-17)5-2-8-30)12-18-15-28(24-21-18)6-3-9-31/h13-15,29-31H,1-12H2

InChI key

VAKXPQHQQNOUEZ-UHFFFAOYSA-N

assay

95%

form

solid

mp

331-336 °C (decomposition)

storage temp.

2-8°C

Quality Level

100

reaction suitability

reagent type: ligand
reaction type: click chemistry

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1 of 4

Este artículo
690112690007254746
Tris(3-hydroxypropyltriazolylmethyl)amine 95%

Sigma-Aldrich

762342

Tris(3-hydroxypropyltriazolylmethyl)amine

(R)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol 95% (HPLC)

Sigma-Aldrich

690112

(R)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol

(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol 95% (HPLC)

Sigma-Aldrich

690007

(S)-3,3′-Bis(2,4,6-triisopropylphenyl)-1,1′-bi-2-naphthol

Triisopropanolamine 95%

Sigma-Aldrich

254746

Triisopropanolamine

assay

95%

assay

95% (HPLC)

assay

95% (HPLC)

assay

95%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

reaction suitability

reaction type: click chemistry

reaction suitability

-

reaction suitability

-

reaction suitability

-

mp

331-336 °C (decomposition)

mp

-

mp

-

mp

48-52 °C (lit.)

form

solid

form

solid

form

solid

form

-

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

Application

Effective ligand for copper-catalyzed azide-alkyne cycloadditions (CuAAC).
Tris(3-hydroxypropyltriazolylmethyl)amine is a water-soluble copper(I) stabilizing ligand mainly used in copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC) reactions.[1][2]

related product

Referencia del producto
Descripción
Precios

906301

BTTES

906328

BTTAA, ≥95%

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCZ4774
MKCZ3739
MKCZ2406
MKCX9390
MKCX6851

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Vu Hong et al.
Bioconjugate chemistry, 21(10), 1912-1916 (2010-10-05)
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, optimized for biological molecules in aqueous buffers, has been shown to rapidly label mammalian cells in culture with no loss in cell viability. Metabolic uptake and display of the azide derivative of N-acetylmannosamine developed
Ofer Stempler et al.
Nature communications, 8(1), 315-315 (2017-08-23)
Bacteria have developed various mechanisms by which they sense, interact, and kill other bacteria, in an attempt to outcompete one another and survive. Here we show that Bacillus subtilis can kill and prey on Bacillus megaterium. We find that Bacillus
Patrik Fladischer et al.
Biotechnology journal, 14(3), e1800125-e1800125 (2018-06-05)
The site-specific incorporation of non-canonical amino acids (ncAAs) at amber codons requires an aminoacyl-tRNA synthetase and a cognate amber suppressor tRNA (tRNACUA ). The archaeal tyrosyl-tRNA synthetase from Methanocaldococcus jannaschii and the pyrrolysyl-tRNA synthetase (PylRS) from Methanosarcina mazei have been
A two-component'double-click'approach to peptide stapling.
Lau YH, et al.
Nature Protocols, 10(4), 585-585 (2015)
Sheng Wang et al.
The Journal of pathology, 243(1), 78-88 (2017-06-29)
Protein modification by O-linked β-N-acetylglucosamine (O-GlcNAc) is emerging as an important factor in the pathogenesis of sporadic Alzheimer's disease (AD); however, detailed molecular characterization of this important protein post-translational modification at the proteome level has been highly challenging, owing to
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the recommended storage condition for stock solutions of item 762342, Tris(3-hydroxypropyltriazolylmethyl)amine?

    1 answer

    1. Prepare stock solutions in ddH2O and store them at -20°C. It's important to avoid freeze-thaw cycles.

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1 Review This action will navigate to reviews.
1 of 1 reviewers received a sample product or took part in a promotion

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