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Merck

D2955000

Domperidone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-(5-Chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine

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120 MG

MXP 4,124.00

MXP 4,124.00


Fecha estimada de envío26 de diciembre de 2025Detalles


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Fórmula empírica (notación de Hill):
C22H24ClN5O2
Número CAS:
Peso molecular:
425.91
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

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Nombre del producto

Domperidone, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

SMILES string

Clc1ccc2N(C3CCN(CCCN4C(=O)Nc5ccccc45)CC3)C(=O)Nc2c1

InChI key

FGXWKSZFVQUSTL-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

domperidone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

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Este artículo
D122D2957000Y0001042
Domperidone European Pharmacopoeia (EP) Reference Standard

D2955000

Domperidone

grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

EDQM

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

neat

format

neat

API family

domperidone

API family

-

API family

domperidone

API family

omeprazole

Application

Domperidone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

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Referencia del producto
Descripción
Precios

pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3


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Domperidone.
M C Champion
General pharmacology, 19(4), 499-505 (1988-01-01)
R N Brogden et al.
Drugs, 24(5), 360-400 (1982-11-01)
Domperidone is a dopamine antagonist that does not readily enter the central nervous system. Given parenterally or orally it increases gastric emptying of liquids and increases lower oesophageal sphincter pressure in healthy subjects. The antiemetic and pharmacodynamic profile of domperidone
Badriul Hegar et al.
The Turkish journal of pediatrics, 55(1), 1-7 (2013-05-23)
Gastroesophageal reflux (GER) is a normal physiologic process occurring several times per day in healthy infants. Regurgitation is defined as the passage of refluxed gastric contents into the pharynx or mouth, sometimes with expulsion out of the mouth. There are
Savio C Reddymasu et al.
The American journal of gastroenterology, 102(9), 2036-2045 (2007-05-10)
Domperidone is a dopamine-2 receptor antagonist. It acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine. Unlike metoclopramide, it does not cause any adverse
Luc M Hondeghem
Journal of cardiovascular pharmacology, 61(3), 218-225 (2012-11-29)
Domperidone (antinausea/vomiting agent) was recently shown by several groups to increase sudden cardiac death (SCD). Drug-induced disturbances of cardiac repolarization may be a major mechanism. Experiments were executed in isolated female rabbit hearts perfused for 150 minutes with domperidone 30

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