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Merck

ADORA3

adenosine A3 receptor

Synonimy:
A3AR, AD026, bA552M11.5
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
AB-MECA, solid,
Gatunek
human, rat
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Gatunek
human
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Adenosine, ,
Gatunek
human
Adenosine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
VUF 5574, ,
Gatunek
human
3-Deazaadenosine, ,
Gatunek
rat
Tyramine hydrochloride, ≥98%,
Gatunek
human
(S)-(−)-Bay K8644, ≥98% (HPLC), solid,
Gatunek
human, rat
2-Fluoroadenosine, 97%,
Gatunek
rat, human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ADORA3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
Przeciwciało przeciwko receptorowi adenozyny A3, zewnątrzkomórkowe (n.a. 154-168), Chemicon®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
ELISA
immunocytochemistry

western blot
Monoclonal Anti-ADORA3 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
EHNA hydrochloride, ≥98% (HPLC),
Gatunek
human
Dilazep dihydrochloride, powder,
Gatunek
human
Galangin, autophagy inducing flavonoid,
Gatunek
human, rat
S-(4-Nitrobenzyl)-6-thioinosine, ≥98%, solid,
Gatunek
human
5′-Deoxy-5′-(methylthio)adenosine, ,
Gatunek
human, rat, mouse

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
2-Chloro-2′-deoxyadenosine, antileukemic,
Gatunek
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Gatunek
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Gatunek
human, rat
Adenosine, ≥99%,
Gatunek
human, rat
Theophylline, anhydrous, ≥99%, powder,
Gatunek
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
2-Fluoroadenosine, 97%,
Gatunek
rat, human
2-Iodoadenosine, 97%,
Gatunek
human, rat
2-Fluoroadenine-9-β-D-arabinofuranoside, DNA synthesis and methylation inhibitor,
Gatunek
rat, human
2-Chloroadenosine, ,
Gatunek
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
Gatunek
human, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ADORA3,
Gatunek
human
MISSION® esiRNA, targeting human TMIGD3,
Gatunek
human