75746

Sodium dodecyl sulfate

≥99.0% (GC), dust-free pellets

• Synonim(y): Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Wzór liniowy: CH₃(CH₂)₁₁OSO₃Na
• Numer CAS: 151-21-3
• Masa cząsteczkowa: 288.38
• Beilstein: 3599286
• Numer EC: 205-788-1
• Numer MDL: MFCD00036175
• eCl@ss: 39093306
• Identyfikator substancji w PubChem: 329766677
• NACRES: NA.25

Właściwości

• opis: anionic
• Poziom jakości: 200
• Próba: ≥99.0% (GC)
• forma: rod
• masa cząsteczkowa: average mol wt 18,000
• liczba agregacji: 62
• strata: ≤5% loss on drying
• CMC: 7-10 (lit.)
• mp: 204-207 °C (lit.)
• temp. przejścia: cloud point >100 °C(lit.)
• rozpuszczalność: H₂O: soluble 0.29 gm in 10ml, clear, colorless; H₂O: 0.1 M at 20 °C, clear, colorless
• ślady anionów: chloride (Cl^-): ≤200 mg/kg
• ślady kationów: Ca: ≤25 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤200 mg/kg; Mg: ≤20 mg/kg; Mn: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• HLB: 40(lit.)
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Opis

Opis ogólny

Sodium dodecyl sulfate (SDS) is an organic sodium salt used as both a detergent and a protein denaturant in biochemical research. Its unique structure includes a long-chain aliphatic group with a negatively charged sulfate, making it an effective agent for denaturing proteins. This property is especially valuable in electrophoresis, a technique used to separate and analyze macromolecules like proteins. SDS, with its negative charge, interacts with proteins and lipids to create micellar structures, aiding in solubilizing and stabilizing these biomolecules.

Zastosowanie

Sodium dodecyl sulfate (SDS) has been used:

• as a negatively charged surfactant to study its effects on filtration flux and membrane fouling during the microfiltration of the surfactant-stabilized oil emulsion
• as a component of plant extraction buffer, and transferring buffer for western blot
• as a component of 5× Laemmli sample buffer (5× LB) and 10× SDS running buffer for sodium dodecyl-sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblot

Anionic detergent

Działania biochem./fizjol.

Sodium dodecyl sulfate (SDS) effectively binds to the positively charged and the hydrophobic residues of proteins via sulfate groups and alkyl chains. It functions as a vital detergent in the domain of structural biology and protein folding/unfolding studies. SDS can stimulate the creation of α-helices in a protein structure. It has the ability to promote cooperative unfolding in several proteins including bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations. 

Cechy i korzyści

• Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
• Tested for trace levels of Anions and Cations
• High-purity product ideal for biochemical research purposes

Informacja o środkach bezpieczeństwa

• piktogramy: GHS05,GHS07
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H302 - H315 - H318 - H412
• Zwroty wskazujące środki ostrożności: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Klasyfikacja zagrożeń: Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2
• Kod klasy składowania: 11 - Combustible Solids
• WGK: WGK 2
• Temperatura zapłonu °F: 338.0 °F
• Temperatura zapłonu °C: 170 °C
• Środki ochrony indywidualnej: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges