SML0910

TC3.6

≥98% (HPLC)

• Synonim(y): 3-Phenyl-2,4(1H,3H)-quinazolinedithione
• Wzór empiryczny (zapis Hilla): C₁₄H₁₀N₂S₂
• Numer CAS: 16081-93-9
• Masa cząsteczkowa: 270.37
• UNSPSC Code: 41106305
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: light orange to dark orange
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Sc1[n]([c](c3c(n1)cccc3)=S)c2ccccc2
• InChI key: DJJOAJCVIYRELX-UHFFFAOYSA-N

Opis

Biochem/physiol Actions

TC3.6 is a PDE7 selective inhibitor (IC₅₀ = 1.04 μM). In an Experimental Autoimmune Encephalomyelitis (EAE) murine model, TC3.6 reduced levels of IL-17, blocked infiltration of immune cells into the CNS and elevated levels of the Treg marker Foxp3. TC3.6 also enhances survival and differentiation of oligodendrocyte precursor cells.

TC3.6 is a PDE7 selective inhibitor.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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Informacja o środkach bezpieczeństwa

• Kody zagrożeń: H413
• Ostrzeżenia: P273 - P501
• Hazard Classifications: Aquatic Chronic 4
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable