V4765

Valnoctamide

≥98% (NMR)

• Synonim(y): 2-ethyl-3-methyl-pentanamide, Axiquel, Nirvanil
• Wzór empiryczny (zapis Hilla): C₈H₁₇NO
• Numer CAS: 4171-13-5
• Masa cząsteczkowa: 143.23
• NACRES: NA.77
• PubChem Substance ID: 329829054
• UNSPSC Code: 12352200
• MDL number: MFCD00868184
• Assay: ≥98% (NMR)
• Form: powder
• Storage condition: desiccated

Właściwości

• Quality Segment: 100
• assay: ≥98% (NMR)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: room temp
• SMILES string: CCC(C)C(CC)C(N)=O
• InChI: 1S/C8H17NO/c1-4-6(3)7(5-2)8(9)10/h6-7H,4-5H2,1-3H3,(H2,9,10)
• InChI key: QRCJOCOSPZMDJY-UHFFFAOYSA-N

Opis

Application

Valnoctamide has been used:

• as a mood stabilizer to study its anti-cytomegalovirus (anti-CMV) effects in newborn mice brain
• as a hypnotic sedative to study its cytotoxic effects on oligodendrocyte precursor cells (OPCs) and human oligodendroglioma cell line (HOG)
• as a mood stabilizer to study its effects on inhibition of human cytomegalovirus

Biochem/physiol Actions

Valproic acid (VPA) and derivatives such as valpromide and valnoctamide are anti-convulsant, mood stabilizing drugs, believed to function as indirect GABA agonists by inhibiting the transamination of GABA.

Valnoctamide exhibits anti-cytomegalovirus (anti-CMV) properties. It has therapeutic effects against status epilepticus (SE) and neuropathic pain. Valnoctamide also shows therapeutic effects against bipolar disorders.

Features and Benefits

This compound is featured on the Glutamate/GABA Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS07
• Słowo ostrzegawcze: Warning
• Kody zagrożeń: H302
• Ostrzeżenia: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable