If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
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Informacje o tej pozycji
grade
pharmaceutical primary standard
agency
USP
vapor density
2.07 (vs air)
API family
glacial acetic acid
form
liquid
autoignition temp.
800 °F
expl. lim.
16 %, 92 °F, 4 %, 59 °F
manufacturer/tradename
USP
technique(s)
gas chromatography (GC): suitable
refractive index
n20/D 1.371 (lit.)
bp
117-118 °C (lit.)
mp
16.2 °C (lit.)
density
1.04 g/mL at 25 °C (lit.)
application(s)
USP Biologics
pharmaceutical (small molecule)
pharmaceutical
format
neat
SMILES string
[F2C(F2C)13F3C]C(O)=O
InChI
1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
InChI key
QTBSBXVTEAMEQO-UHFFFAOYSA-N
General description
Glacial acetic acid is a commonly used solvent and pH modifier in peptide synthesis and purification. It may be present as a residual process reagent. The USP standard is used to quantify acetic acid levels in peptide APIs and assess formulation stability.
The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Application
Further information is available in the general chapter, 503- ACETIC ACID IN PEPTIDES, USP43-NF38 - 6741 of the USP (United States Pharmacopeia).
Other Notes
1 of 1
Ta pozycja | ||
|---|---|---|
| description United States Pharmacopeia (USP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material | description analytical standard |
| manufacturer/tradename USP | manufacturer/tradename - | manufacturer/tradename - |
| grade pharmaceutical primary standard | grade certified reference material, pharmaceutical secondary standard | grade analytical standard |
| application(s) USP Biologics | application(s) pharmaceutical | application(s) cleaning products |
| form liquid | form - | form - |
| format neat | format neat | format neat |
| technique(s) gas chromatography (GC): suitable | technique(s) gas chromatography (GC): suitable, HPLC: suitable | technique(s) gas chromatography (GC): suitable, HPLC: suitable, chromatography: suitable |
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Słowo ostrzegawcze
Danger
Kody zagrożeń
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
Klasa składowania
3 - Flammable liquids
Temperatura zapłonu (°F)
102.2 °F - closed cup
Temperatura zapłonu (°C)
39 °C - closed cup
Wykazy regulacyjne
Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.
64-19-7
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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