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1091108

USP

Capsaicin

United States Pharmacopeia (USP) Reference Standard

Synonim(y):

8-Methyl-N-vanillyl-trans-6-nonenamide

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Informacje o tej pozycji

Wzór liniowy:
(CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
Numer CAS:
Masa cząsteczkowa:
305.41
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2816484
eCl@ss:
25140904
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grade

pharmaceutical primary standard

agency

USP

API family

capsaicin

manufacturer/tradename

USP

mp

62-65 °C (lit.)

application(s)

pharmaceutical (small molecule)
pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O

InChI

1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+

InChI key

YKPUWZUDDOIDPM-SOFGYWHQSA-N

Gene Information

human ... TRPV1(7442)

General description

Find answers to frequently asked questions on USP products in USP FAQs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Capsaicin USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for the assay, identification, composition and strength analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Capsaicin
  • Capsicum Oleoresin
  • Capsicum
  • Ginger Tincture

Biochem/physiol Actions

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers.
Prototype vanilloid receptor agonist; neurotoxin. Active component of chili peppers.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.
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grade

pharmaceutical primary standard

grade

primary reference standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

manufacturer/tradename

USP

manufacturer/tradename

PhytoLab

manufacturer/tradename

EDQM

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)
pharmaceutical

application(s)

food and beverages

application(s)

pharmaceutical (small molecule)
pharmaceutical

application(s)

pharmaceutical
pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

API family

capsaicin

API family

-

API family

capsaicin

API family

capsaicin

mp

62-65 °C (lit.)

mp

62-65 °C (lit.)

mp

62-65 °C (lit.)

mp

62-65 °C (lit.)


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Słowo ostrzegawcze

Danger

Hazard Classifications

Acute Tox. 2 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Narządy docelowe

Respiratory system

Klasa składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Temperatura zapłonu (°F)

235.4 °F - closed cup

Temperatura zapłonu (°C)

113 °C - closed cup



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Certyfikaty analizy (CoA)

Lot/Batch Number

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Questions

  1. What is the % purity of this chemical ?

    1 answer
    1. The current Lot has a purity value of 98.9%. This information is published in the supplier Certificate of Analysis. Please see the link below to review:
      https://static.usp.org/pdf/EN/referenceStandards/certificates/1091108-R18530.pdf

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