1615138

Trifluorooctan sodu

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): Sodium trifluoroacetate, Trifluoroacetic acid sodium salt
• Wzór liniowy: CF₃COONa
• Numer CAS: 2923-18-4
• Masa cząsteczkowa: 136.01
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751130
• MDL number: MFCD00013217
• Beilstein/REAXYS Number: 3597949

Właściwości

• grade: pharmaceutical primary standard
• agency: USP
• API family: sodium trifluoroacetate
• form: powder
• manufacturer/tradename: USP
• mp: 205-207 °C (dec.) (lit.)
• density: 1.49 g/mL (lit.)
• application(s): USP Biologics; pharmaceutical (small molecule); pharmaceutical; pharmaceutical
• format: neat
• SMILES string: [Na+].[O-]C(=O)C(F)(F)F
• InChI: 1S/C2HF3O2.Na/c3-2(4,5)1(6)7;/h(H,6,7);/q;+1/p-1
• InChI key: UYCAUPASBSROMS-UHFFFAOYSA-M

Opis

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Sodium trifluoroacetate (TFA) is a commonly encountered residual reagent or counter-ion in peptide synthesis and purification. It is often present due to the use of trifluoroacetic acid in cleavage and purification steps. The USP standard supports the identification and quantification of TFA in peptide active pharmaceutical ingredients (APIs) and formulations.

The USP biologics peptides category encompasses a diverse range of therapeutic peptides that are essential in managing various medical conditions. These peptides, typically consisting of amino acid sequences of 40 residues or less, are critical for the development of high-quality medicines. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of peptide therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Sodium trifluoroacetate reference standard intended for use in specified quality tests and assays.

Also used to prepare trifluoroacetic acid (TFA) Stock solution to determine the amount of trifluoroacetic acid (TFA) in peptides according to the given below general chapter of United States Pharmacopeia (USP):

• 〈503.1〉 Trifluoroacetic acid (TFA) in peptides

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS09
• Kody zagrożeń: H411
• Ostrzeżenia: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Klasa składowania: 11 - Combustible Solids
• Co się dzieje?: WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable