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ABL2 (38-end), active, His tagged human

Name: ABL2 (38-end), active, His tagged human
Brand: SIGMA
Price: 432 USD
Availability: InStock

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

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Synonym(s):

ABLL, ARG

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10 μg	Check Cart for Availability	$432.00

About This Item

NACRES:

NA.77

UNSPSC Code:

12352202

Specific activity:

1035-1401 nmol/min·mg

Assay:

≥70% (SDS-PAGE)

Recombinant:

expressed in baculovirus infected Sf9 cells

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Properties

recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

200

product line

PRECISIO^® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

1035-1401 nmol/min·mg

mol wt

~132 kDa

UniProt accession no.

P42684

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ABL2(27)

Description

Biochem/physiol Actions

ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas. Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified. The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments.

Physical form

Supplied in 50mM NaPhosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1mM PMSF, 0.2 mM DTT, 25% glycerol.
.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	SRP5279	SAB4300273	SRP5067
Sigma-Aldrich A0733 ABL2 (38-end), active, His tagged human	Sigma-Aldrich SRP5279 ABL1, active, His tagged human	Sigma-Aldrich SAB4300273 Anti-phospho-ABL1/ABL2 (pTyr^393/429) antibody produced in rabbit	Sigma-Aldrich SRP5067 PKC ε , active, GST tagged human
description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description PRECISIO^®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution	description affinity isolated antibody	description PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
specific activity 1035-1401 nmol/min·mg	specific activity 663-1024 nmol/min·mg	specific activity -	specific activity 1033-1398 nmol/min·mg
Gene Information human ... ABL2(27)	Gene Information human ... ABL1(25)	Gene Information human ... ABL1(25), ABL2(27)	Gene Information human ... PRKCE(5581)
assay ≥70% (SDS-PAGE)	assay ≥70% (SDS-PAGE)	assay -	assay ≥70% (SDS-PAGE)
form buffered aqueous glycerol solution	form buffered aqueous glycerol solution	form buffered aqueous solution	form buffered aqueous glycerol solution
recombinant expressed in baculovirus infected Sf9 cells	recombinant expressed in baculovirus infected Sf9 cells	recombinant -	recombinant expressed in baculovirus infected Sf9 cells
storage temp. −70°C	storage temp. −70°C	storage temp. −20°C	storage temp. −70°C

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Codes

H315,H319,H360D

Precautionary Statements

P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number

SLBC4477V

SLBB6665V

SLBC0612V

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