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B3306

Bisindolylmaleimide IV

≥98% (TLC), solid

Synonym(s):

Ro 31-6233

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Size/SKUAvailabilityPrice
1 mg

Estimated to ship onOctober 19, 2026fromSAINT LOUIS

$119.00

About This Item

Empirical Formula (Hill Notation):
C20H13N3O2
CAS Number:
Molecular Weight:
327.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352111
MDL number:
eCl@ss:
32150917
Assay:
≥98% (TLC)
Form:
solid

$119.00


Estimated to ship onOctober 19, 2026Details


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biological source

synthetic (organic)

Quality Segment

assay

≥98% (TLC)

form

solid

color

dark red

solubility

DMSO: soluble, methanol: soluble

storage temp.

−20°C

SMILES string

O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c4c[nH]c5ccccc45

InChI

1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)

InChI key

DQYBRTASHMYDJG-UHFFFAOYSA-N

Gene Information

human ... CDK2(1017), EGFR(1956)
rat ... Prkca(24680)

Biochem/physiol Actions

Bisindolylmaleimides (BIM) comprises a group of 11 compounds from BIM-I to BIM-XI. BIMs act as an inhibitor of protein kinase C (PKC). They are derived from staurosporine. BIM IX due to its proapoptotic functionality could be useful in targeting tumor proliferation.

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This Item
203290203293B3056
description

≥98% (TLC), solid

description

A highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor (IC50 = 10 nM) that is structurally similar to staurosporine.

description

InSolution, ≥95%, protein kinase C (PKC) inhibitor

description

≥97% (Mixture of 2 isomers)

form

solid

form

solid

form

liquid

form

powder

assay

≥98% (TLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥97% (Mixture of 2 isomers)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

methanol: soluble, DMSO: soluble

solubility

DMSO: 10 mg/mL

solubility

-

solubility

ethanol: soluble, DMSO: soluble

color

dark red

color

deep orange

color

-

color

-


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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