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D5294

Dilazep dihydrochloride

powder

Synonym(s):

ASTA C 4898, Cormelian, N,N′-bis(3-[3,4,5-Trimethoxybenzoyloxy]propyl)homopiperazine dihydrochloride

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Size/SKUAvailabilityPrice
50 mg

Available to ship TODAYfromMILWAUKEE

$356.00

About This Item

Empirical Formula (Hill Notation):
C31H44N2O10 · 2HCl
CAS Number:
20153-98-4
Molecular Weight:
677.61
NACRES:
NA.77
PubChem Substance ID:
24278372
UNSPSC Code:
12352200
EC Number:
243-548-8
MDL number:
MFCD00133267
Form:
powder

$356.00

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form

powder

Quality Segment

color

white

solubility

H2O: 10 mg/mL

storage temp.

2-8°C

SMILES string

Cl[H].Cl[H].COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2

InChI

1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H

InChI key

VILIWRRWAWKXRW-UHFFFAOYSA-N

Gene Information

General description

Dilazep comprises central cyclic diamine and phenyl rings connected via alkyl linkers.

Application

Dilazep dihydrochloride has been used in estrogen receptor (ERα) antagonistic assay. It has also been used as an equilibrative nucleoside transporter inhibitor (ENT 1 and 2) in cancer cell lines.

Biochem/physiol Actions

Dilazep is a equilibrative nucleoside transporter 1 (ENTs) inhibitor. It is an antianginal drug and an effective coronary vasodilator. Dilazep elicits anti-albuminuric effects and is an anti-platelet agent. It is a potent adenosine uptake inhibitor and suppresses effects of ischemia.

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This Item
T4577Y00000541016000
Dilazep dihydrochloride powder

Sigma-Aldrich

D5294

Dilazep dihydrochloride

Terodiline hydrochloride ≥98% (HPLC), solid

Sigma-Aldrich

T4577

Terodiline hydrochloride

Alprostadil European Pharmacopoeia (EP) Reference Standard

Y0000054

Alprostadil

Alprostadil United States Pharmacopeia (USP) Reference Standard

USP

1016000

Alprostadil

description

powder

description

≥98% (HPLC), solid

description

European Pharmacopoeia (EP) Reference Standard

description

United States Pharmacopeia (USP) Reference Standard

form

powder

form

solid

form

-

form

-

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 10 mg/mL

solubility

DMSO: >20 mg/mL

solubility

-

solubility

-

color

white

color

white to off-white

color

-

color

-

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

Gene Information

human ... CACNA1A(773), CACNA1B(774), CACNA1C(775), CACNA1D(776), CACNA1E(777), CACNA1F(778), CACNA1G(8913), CACNA1H(8912), CACNA1I(8911), CACNA1S(779), CACNA2D1(781), CACNA2D2(9254), CACNA2D3(55799), CACNA2D4(93589), CACNB1(782), CACNB2(783), CACNB3(784), CACNB4(785), CACNG1(786), CACNG2(10369), CACNG3(10368), CACNG4(27092), CACNG5(27091), CACNG6(59285), CACNG7(59284), CACNG8(59283), CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Gene Information

human ... PTGER1(5731), PTGER2(5732)

Gene Information

human ... PTGER1(5731), PTGER2(5732)

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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