Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

D6571

3′,4′-Dimethoxyflavone

Synonym(s):

2-(3,4-Dimethoxyphenyl)chromen-4-one, 3′,4′-DMF

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$101.00
$85.85
25 mg

Available to ship TODAYfromMILWAUKEE

$383.00

About This Item

Empirical Formula (Hill Notation):
C17H14O4
CAS Number:
4143-62-8
Molecular Weight:
282.29
NACRES:
NA.77
PubChem Substance ID:
329798831
UNSPSC Code:
12352200
MDL number:
MFCD00143009
Assay:
≥98% (HPLC)
Form:
powder

$85.85

List Price$101.00Save 15%
Web-Only Promotion

Available to ship TODAYDetails

​
Request a Custom Order
​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥98% (HPLC)

Quality Segment

100

form

powder

color

white to off-white

solubility

DMSO: ≥20 mg/mL

storage temp.

room temp

SMILES string

COc1ccc(cc1OC)C2=CC(=O)c3ccccc3O2

InChI

1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3

InChI key

ZGHORMOOTZTQFL-UHFFFAOYSA-N

Application

3′,4′-Dimethoxyflavone has been used in urease inhibition assay.

Biochem/physiol Actions

3′,4′-dimethoxyflavone is a competitive antagonist of the AhR that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. The compound blocks transformation of the cytosolic AhR complex, and formation of nuclear AhR complexes.
3′,4′-dimethoxyflavone is a competitive antagonist of the aryl hydrocarbon receptor (AhR) that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines.
3′,4′-Dimethoxyflavone is a flavone compound, which has the ability to prevent the production and accumulation of poly (ADP-ribose) (PAR) polymer. It guards against N-methyl-D-aspartate (NMDA) toxicity in cortical neurons. 3′,4′-Dimethoxyflavone is a member of the class of plant-derived polyphenolic flavonoids. It is known to have antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidemic and neuroprotective or neurotrophic effects.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
T4080C8249SML0688
3′,4′-Dimethoxyflavone

Sigma-Aldrich

D6571

3′,4′-Dimethoxyflavone

6, 2′, 4′-trimethoxyflavone ≥98% (HPLC)

Sigma-Aldrich

T4080

6, 2′, 4′-trimethoxyflavone

Cardamonin ≥98% (HPLC)

Sigma-Aldrich

C8249

Cardamonin

PO1 ≥98% (HPLC)

Sigma-Aldrich

SML0688

PO1

description

-

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: >5 mg/mL

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 1 mg/mL, clear (warmed)

color

white to off-white

color

yellow

color

light yellow to dark brown

color

faintly pink to red

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters