Each vial contains approximately 2.5 mg protein. The minimum protein concentration is 2.5 mg/mL. A survey of recent lots indicates a consistent concentration of 5.0 mg/mL. The minimum activity of this enzyme is 1 unit per milligram and varies considerably from lot to lot. This value is reported in the product Certificate of Analysis. Please see the link below to review a sample or lot-specific Certificate:
https://www.sigmaaldrich.com/product/sigma/m7441#product-documentation
M7441
Monoamine Oxidase B human
recombinant, expressed in baculovirus infected BTI insect cells
Synonym(s):
MAO-B
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| Size/SKU | Availability | Price |
|---|---|---|
1 vial | Check Cart for Availability | $636.00 |
5 x 1 vial | Check Cart for Availability | $2,420.00 |
About This Item
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
MDL number:
eCl@ss:
32160703
Specific activity:
≥1 units/mg protein
Assay:
≥2.5 mg/mL (Lowry)
Biological source:
human plasma
Recombinant:
expressed in baculovirus infected BTI insect cells
Concentration:
≥2.5 mg/mL
$636.00
Check Cart for Availability
Quality Segment
biological source
human plasma
recombinant
expressed in baculovirus infected BTI insect cells
assay
≥2.5 mg/mL (Lowry)
form
liquid
specific activity
≥1 units/mg protein
packaging
vial of ~2.5 mg
concentration
≥2.5 mg/mL
optimum pH
7.4
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... MAOB(4129)
General description
Substrate Specificity
a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2
a secondary aliphatic amine + O2 + H2O = a primary amine + an aldehyde + H2O2
Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs.
Application
Biochem/physiol Actions
MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.
Other Notes
kynuramine deamination activity: One unit will deaminate 1 nanomole of kynuramine per minute at pH 7.4 at 37 deg C.
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This Item | |||
|---|---|---|---|
| description recombinant, expressed in baculovirus infected BTI insect cells | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | description - | description affinity isolated antibody |
| Gene Information human ... MAOB(4129) | Gene Information human ... MAOB(4129) | Gene Information human ... MAOB(4129) | Gene Information human ... MAOB(4129) |
| assay ≥2.5 mg/mL (Lowry) | assay - | assay - | assay - |
| form liquid | form buffered aqueous glycerol solution | form liquid | form buffered aqueous solution |
| recombinant expressed in baculovirus infected BTI insect cells | recombinant - | recombinant - | recombinant - |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. - |
| storage temp. −70°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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