PLA0141

Rabbit anti-Phospho MCM2 (S40/S41) Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): BM28, CCNL1, CDCL1, D3S3194, DFNA70, KIAA0030, MCM2 minichromosome maintenance deficient 2, cdc19, cell devision cycle-like 1, cyclin-like 1, minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin), minichromosome maintenance deficient 2 (mitotin), minichromosome maintenance protein 2 homolog, mitotin, mitotin (S. cerevisiae), nuclear protein BM28
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: FACS, IHC, WB
• Citations: -

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• technique(s): flow cytometry: 0.1 μg, immunohistochemistry: 1:100- 1:500, western blot: 1:1,000- 1:5,000
• accession no.: NP_004517.2
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: phosphorylation (pSer40/pSer41)
• Gene Information: human ... MCM2(4171)

Description

Immunogen

Immunogen was a synthetic di-phosphorylated peptide, which represented a portion of human minichromosomal maintenance deficient 2 surrounding Serines 40 and 41 according to the numbering given in entry NP_004517.2 (GeneID 4171).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable