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SML0902

MONNA

≥98% (HPLC)

Synonym(s):

N-((4-Methoxy)-2-naphthyl)-5-nitroanthranilic acid

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5 mg

Estimated to ship TODAYfromMILWAUKEE

$119.00
25 mg
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$462.00

About This Item

Empirical Formula (Hill Notation):
C18H14N2O5
Molecular Weight:
338.31
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder

$119.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

Biochem/physiol Actions

MONNA is a TMEM16A (ANO1) calcium-activated chloride channel blocker.
MONNA is a TMEM16A (ANO1) calcium-activated chloride channel blocker. MONNA blocks rhTMEM16A (ANO1) channel currents in HEK293 cells with and IC50 of 1.27 μM. The compound MONNA does not affect related human or mouse chloride channels bestrophin-1, CLC2 and CFTR at concentrations up to 10 μM.
MONNA (benzbromarone (Benzb) and N-((4-methoxy)-2-naphthyl)-5-nitroanthranilic acid) is a TMEM16A antagonists. It affects the liberation of sarcoplasmic reticulum (SR) calcium in human airway smooth muscle cells.


Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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