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SML2283

Lenalidomide

≥98% (HPLC), powder, cereblon binder

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Synonym(s):

Lenalidomide, 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole, 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidin-2,6-dione, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, CC 5013, CC-5013

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Size/SKUAvailabilityPrice
100 mg

Available to ship TODAYfromMILWAUKEE

$65.50
250 mg

Available to ship TODAYfromMILWAUKEE

$142.00

About This Item

Empirical Formula (Hill Notation):
C13H13N3O3
CAS Number:
Molecular Weight:
259.26
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

$65.50

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Product Name

Lenalidomide, ≥98% (HPLC)

ligand

lenalidomide

assay

≥98% (HPLC)

form

powder

reaction suitability

reagent type: ligand

technique(s)

targeted protein degradation: suitable

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N

InChI

1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)

InChI key

GOTYRUGSSMKFNF-UHFFFAOYSA-N

Biochem/physiol Actions

Lenalidomide, a derivative of thalidomide, is an immunomodulatory agent that is approved drug for treatment of multiple myeloma. Apparently Lenalidomide is a ligand of ubiquitin E3 ligase cereblon that induces the enzyme to degrade the Ikaros transcription factors IKAROS family zinc finger 1 (IKZF1) and IKZF3. Lenalidomide possess pleiotropic antitumor effects. It is used in the treatment of 5q-deletion associated myelodysplastic syndrome (del(5q)-MDS).

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This Item
901558P0018T144
description

≥98% (HPLC)

description

≥95%

description

≥98% (HPLC)

description

≥98%, powder

assay

≥98% (HPLC)

assay

≥95%

assay

≥98% (HPLC)

assay

≥98%

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

DMSO: ≥14 mg/mL

solubility

DMSO: 20 mg/mL, clear

color

white to beige

color

-

color

yellow

color

white

reaction suitability

reagent type: ligand

reaction suitability

reagent type: ligand

reaction suitability

reagent type: ligand

reaction suitability

reagent type: ligand


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Pictograms

Health hazard

Signal Word

Danger

Hazard Codes

Hazard Classifications

Repr. 1B - STOT RE 2

Target Organs

Blood

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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Questions

  1. What are the preparation and storage instructions for Lenalidomide?

    1 answer
    1. In the powder form, this product is stored at 2-8°C. The material is soluble at 2 mg/mL in DMSO. The stability of this product in solution has not been determined. Other sources indicate that aqueous solutions should be prepared fresh daily. This information has not been validated.

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