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Merck

328650

叔丁醇钾 溶液

1.0 M in THF

别名:

2-甲基丙-2-醇钾溶液, 叔丁醇钾

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50 ML

$100.00

500 ML

$423.00

$100.00


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线性分子式:
(CH3)3COK
化学文摘社编号:
分子量:
112.21
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3556712

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产品名称

叔丁醇钾 溶液, 1.0 M in THF

InChI

1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1

SMILES string

[K+].CC(C)(C)[O-]

InChI key

LPNYRYFBWFDTMA-UHFFFAOYSA-N

form

liquid

reaction suitability

core: potassium

concentration

1.0 M in THF

density

0.902 g/mL at 25 °C

Quality Level

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702757659878398195
form

liquid

form

liquid

form

solid

form

liquid

concentration

1.0 M in THF

concentration

2 M in THF

concentration

-

concentration

1.0 M in THF

density

0.902 g/mL at 25 °C

density

0.920 g/mL at 25 °C

density

-

density

0.888 g/mL at 25 °C

reaction suitability

core: potassium

reaction suitability

-

reaction suitability

core: potassium

reaction suitability

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

Application

丁二氧化钾溶液(t-BuOK)可用于:
  • 作为菜籽油与乙酸甲酯酯化反应的催化剂。
  • 在温和条件下促进N-苯基氨基酸衍生的酰化铵的 Sommelet-Hauser 重排反应。
  • 作为化学气相沉积法合成 KNbO3 铁电薄膜的金属有机前驱体。
  • 制备 3-钾肟基吡啶催化剂。
  • 作为强醇基试剂。

General description

叔丁醇钾溶液是一种强非亲核碱。它能够使碳和其他布朗斯台德酸去质子化。叔丁醇中的试剂溶液可以通过使无水醇与钾在氮气氛中反应来制备。

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

存储类别

4.3 - Hazardous materials which set free flammable gases upon contact with water

wgk

WGK 1

flash_point_f

-2.2 °F - closed cup

flash_point_c

-19 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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One-step methodology for the synthesis of FA picolinyl esters from intact lipids.
Destaillats F and Angers P
Journal of the American Oil Chemists' Society, 79(3), 253-256 (2002)
Eiji Tayama et al.
Organic & biomolecular chemistry, 6(20), 3673-3680 (2008-10-10)
The Stevens rearrangement of N-allylic alpha-aryl amino acid-derived ammonium salts and the Sommelet-Hauser rearrangement of N-benzylic alpha-alkyl amino acid-derived ammonium salts are shown to proceed with remarkably high levels of diastereoselectivity. The methods presented in this work provide new routes
Wen-Sen He et al.
Bioresource technology, 114, 1-5 (2012-04-03)
The effects of solvents with different log P values, and of lipases on the synthesis of water-soluble plant stanol derivatives were investigated. Results showed that conversion in solvents with log P<0.37 was mainly controlled by the hydrophobicity of the solvent
Brian C Anderson et al.
Biomaterials, 23(22), 4345-4352 (2002-09-11)
Several homopolymers and copolymers of 2-(diethylamino)ethyl methacrylate (DEAEM) and poly(ethylene glycol) methyl ether methacrylate (PEGMEM) were synthesized using anionic polymerization initiated by potassium t-butoxide. The polymers were characterized by average molecular weight, polydispersity and monomeric unit composition. A very narrow
Huaiqing Zhao et al.
Chemical communications (Cambridge, England), 49(23), 2323-2325 (2013-02-14)
A macrocyclic aromatic pyridone pentamer was shown to catalyze highly efficient transition-metal-free arylations of unactivated aromatic C-H bonds with aryl iodides and bromides in the presence of potassium tert-butoxide.

商品

The properties of many devices are limited by the intrinsic properties of the materials that compose them.

Questions

1–10 of 10 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Potassium tert-butoxide solution in THF 1M solution is bottle with sure-seal or not?

    1 answer
    1. Yes, the 50mL, 500mL, and 2L sizes are packaged in amber glass bottles with a Sure/Seal cap. The 20L size is packaged in a steel drum.

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  4. What type of container does this ship in? 328650-20L

    1 answer
    1. Item 328650-20L is packaged in a Carbon Steel Drum that includes a 2-in. and a 3/4-in. opening. Each opening is capped and sealed with a polypropylene tamper-evident seal. See the attached image below.

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  5. How should Product 328650, Potassium tert-butoxide solution, be stored?

    1 answer
    1. Room temperature storage is acceptable for this solution but we would recommend storing this product under nitrogen. The solution can decompose upon exposure to air or moisture. It also can absorb carbon dioxide from the air which will affect quality of the product.

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  6. What gloves can I use to work with Product 328650, Potassium tert-butoxide solution?

    1 answer
    1. We would recommend using Neoprene gloves such as Z402435, Z403407, Z402443, or Z402427.

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  7. Does the Tetrahydrofuran used to make Product 328650, Potassium tert-butoxide solution, contain a stabilizer?

    1 answer
    1. Yes, the THF contains about 0.025% butylated hydroxytoluene (BHT) as a stabilizer.

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  8. What is the purity of Product 328650, Potassium tert-butoxide solution?

    1 answer
    1. We do not perform overall purity testing on this solution. The product is prepared with reagent grade potassium tert-butoxide and then titrated  with hydrochloric acid to define the concentration during the quality control analysis.

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  9. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  10. How do I remove Product 328650, Potassium tert-butoxide solution, from the Sure-Seal bottle?

    1 answer
    1. The Sure-Seal bottle has a septum held in place with a metal crimp cap. We would recommend removing the product by piercing the septum and withdrawing the liquid through a syringe to reduce the compound's exposure to air and moisture. We offer a line of non-coring syringe needles that are ideal for piercing septa.

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