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Merck

A0365900

阿米卡星 硫酸酯

European Pharmacopoeia (EP) Reference Standard

别名:

阿米卡星 二硫酸盐

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200 MG

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关于此项目

经验公式（希尔记法）:
C22H43N5O13 · 2H2SO4
化学文摘社编号:
39831-55-5
分子量:
781.76
Beilstein:
6172633
MDL號碼:
MFCD00167475
分類程式碼代碼:
41116107
PubChem物質ID:
329770610
NACRES:
NA.24

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等級

pharmaceutical primary standard

API 家族

amikacin

製造商／商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

SMILES 字串

OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O

InChI

1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;;/m0../s1

InChI 密鑰

FXKSEJFHKVNEFI-GCZBSULCSA-N

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此商品
BP8531019494PHR1860
阿米卡星 硫酸酯 European Pharmacopoeia (EP) Reference Standard

A0365900

阿米卡星 硫酸酯

硫酸阿米卡星 British Pharmacopoeia (BP) Reference Standard

BP853

硫酸阿米卡星

硫酸阿米卡星 United States Pharmacopeia (USP) Reference Standard

USP

1019494

硫酸阿米卡星

硫酸阿米卡星 Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1860

硫酸阿米卡星

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

USP

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical

format

neat

format

neat

format

neat

format

neat

API family

amikacin

API family

amikacin

API family

amikacin

API family

amikacin

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Amikacin sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Warning

危險聲明

H317,H361fd

危險分類

Repr. 2 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J P Clancy et al.
Thorax, 68(9), 818-825 (2013-06-12)
Arikace is a liposomal amikacin preparation for aerosol delivery with potent Pseudomonas aeruginosa killing and prolonged lung deposition. To examine the safety and efficacy of 28 days of once-daily Arikace in cystic fibrosis (CF) patients chronically infected with P aeruginosa.
Anna Belcarz et al.
International journal of pharmaceutics, 454(1), 285-295 (2013-07-16)
Following the quest for new composite materials for bone tissue engineering, a novel elastic hydroxyapatite-glucan composite loaded with two aminoglycoside antibiotics was prepared. The porosity of the composite and the drug release profiles in closed-loop and semi-open systems were tested.
F D Pien et al.
American journal of hospital pharmacy, 38(7), 981-989 (1981-07-01)
The antibiotic spectrum, pharmacology, adverse effects, and therapeutic use of amikacin sulfate are reviewed. Amikacin, a semisynthetic analog of kanamycin, is highly active against most gram-negative bacteria including many gentamicin-resistant strains. Amikacin's pharmacologic properties have been studied extensively in both
Kenneth S Chen et al.
Pediatric blood & cancer, 60(11), 1772-1777 (2013-06-22)
Children undergoing cancer therapy often receive aminoglycosides to treat febrile neutropenia or gram-negative infections. The magnitude of the risk of developing aminoglycoside-induced ototoxicity and the dose threshold at which that risk significantly increases are unknown. Eligible cancer patients received the
Chien-Wen Huang et al.
International journal of antimicrobial agents, 41(3), 218-223 (2013-01-15)
The occurrence of diseases caused by rapidly growing mycobacteria (RGM) is increasing in Taiwan. In this study, the in vitro antimicrobial activities of tigecycline, minocycline, tetracycline and doxycycline were evaluated against 160 clinical RGM isolates, including 34 Mycobacterium abscessus sensu
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