04-1572
抗RNA聚合酶II亚基B1（磷酸化CTD Ser-5）抗体，克隆3E8
clone 3E8, from rat
同義詞:
DNA-directed RNA polymerase II A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA polymerase II subunit B1, RNA-directed RNA
跳轉至
生物源
rat
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
3E8, monoclonal
物種活性
mouse
物種活性（以同源性預測）
human (based on 100% sequence homology)
技術
ChIP: suitable
ELISA: suitable
western blot: suitable
同型
IgG2aκ
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
phosphorylation (pSer5)
基因資訊
human ... POLR2B(5431)
1 of 4
本產品 | 04-1571 | 04-1572-I | 04-1570 |
|---|---|---|---|
| species reactivity mouse | species reactivity mouse | species reactivity mouse | species reactivity mouse |
| biological source rat | biological source rat | biological source rat | biological source rat |
| clone 3E8, monoclonal | clone 3E10, monoclonal | clone 3E8, monoclonal | clone 4E12, monoclonal |
| antibody form purified immunoglobulin | antibody form purified immunoglobulin | antibody form culture supernatant | antibody form purified immunoglobulin |
| technique(s) ChIP: suitable, western blot: suitable, ELISA: suitable | technique(s) ChIP: suitable, ELISA: suitable, western blot: suitable | technique(s) ChIP: suitable, ELISA: suitable, western blot: suitable | technique(s) ChIP: suitable, ELISA: suitable, western blot: suitable |
| Gene Information human ... POLR2B(5431) | Gene Information human ... POLR2B(5431) | Gene Information human ... POLR2B(5431) | Gene Information human ... POLR2B(5431) |
一般說明
免疫原
應用
转录因子
RNA代谢 & 结合蛋白
表观遗传学 & 核功能
表观遗传学 & 核功能
生化／生理作用
外觀
準備報告
分析報告
γ-蛋白磷酸酶（γ-PPase）未处理和处理的NIH/3T3细胞裂解液
蛋白质印迹分析：1 µg/ml该抗体在10 µg γ-PPase未处理和处理的NIH/3T3细胞裂解液上检测到RNA聚合酶II CTD。
其他說明
免責聲明
未找到適合的產品？
試用我們的產品選擇工具.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
相關內容
Cancer is a complex disease manifestation. At its core, it remains a disease of abnormal cellular proliferation and inappropriate gene expression. In the early days, carcinogenesis was viewed simply as resulting from a collection of genetic mutations that altered the gene expression of key oncogenic genes or tumor suppressor genes leading to uncontrolled growth and disease (Virani, S et al 2012). Today, however, research is showing that carcinogenesis results from the successive accumulation of heritable genetic and epigenetic changes. Moreover, the success in how we predict, treat and overcome cancer will likely involve not only understanding the consequences of direct genetic changes that can cause cancer, but also how the epigenetic and environmental changes cause cancer (Johnson C et al 2015; Waldmann T et al 2013). Epigenetics is the study of heritable gene expression as it relates to changes in DNA structure that are not tied to changes in DNA sequence but, instead, are tied to how the nucleic acid material is read or processed via the myriad of protein-protein, protein-nucleic acid, and nucleic acid-nucleic acid interactions that ultimately manifest themselves into a specific expression phenotype (Ngai SC et al 2012, Johnson C et al 2015). This review will discuss some of the principal aspects of epigenetic research and how they relate to our current understanding of carcinogenesis. Because epigenetics affects phenotype and changes in epigenetics are thought to be key to environmental adaptability and thus may in fact be reversed or manipulated, understanding the integration of experimental and epidemiologic science surrounding cancer and its many manifestations should lead to more effective cancer prognostics as well as treatments (Virani S et al 2012).
Active Filters
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務