1.01736

OSTEOMOLL^®

Solution for rapid decalcification (with fixation) for histology

• 分類程式碼代碼: 12352401
• NACRES: NA.21

屬性

• 品質等級: 400
• 形狀: liquid
• IVD: for in vitro diagnostic use
• 顏色: blue
• pH值: <1 (20 °C in H₂O)
• 密度: 1.10 g/mL at 20 °C
• 應用: diagnostic assay manufacturing; hematology; histology
• 儲存溫度: 15-25°C

描述

一般說明

OSTEOMOLL^® - Solution for rapid decalcification (with fixation) for histology, is used for human cell diagnostics and serves to decalcify (demineralize) bone tissue (e. g. punched bone-marrow specimens) and other hard materials and to soften keratinized tissue of human origin, fixing the specimens in the same process.
Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT^® (Product number 1.01728) can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL^®, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and hydrochloric acid. The amount of OSTEOMOLL^® needed is dependent upon on the size, type and thickness of the material. A 30 ml portion of OSTEOMOLL^®, which should completely cover the material, can be used twice if the solution is still clear and not contaminated.
The material must first be cut to a thickness of max. 5 mm and an area of 6 cm2 (= max. Embedding cassette size). Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT^® is color-coded yellow, OSTEOMOLL^® is color-coded blue. Whereby OSTEOSOFT^® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL^® will be used for tissues that are not destined for antibody analysis.
Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. The quantity of OSTEOMOLL^® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

分析報告

Performance test: passes test

法律資訊

OSTEOMOLL is a registered trademark of Merck KGaA, Darmstadt, Germany

OSTEOSOFT is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS08,GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H290,H302 + H332,H314,H317,H335,H341,H350
• 防範說明: P202 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable