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Merck

2011

胆红素

solid, bile pigment, Calbiochem®

同義詞:

胆红素

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關於此項目

經驗公式(希爾表示法):
C33H36N4O6
CAS 編號:
分子量::
584.66
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

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產品名稱

胆红素, Principal pigment of bile and one of the major end products of hemoglobin decomposition.

品質等級

描述

RTECS - DU3038000
Merck USA index - 14, 1218

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
protect from light

顏色

red-brown

溶解度

chloroform: 1 mg/mL
alkaline solution: soluble

運輸包裝

ambient

儲存溫度

10-30°C

SMILES 字串

[nH]1c(c(c(c1\C=C4/NC(=O)C(=C/4C)C=C)C)CCC(=O)O)Cc2[nH]c(c(c2CCC(=O)O)C)\C=C3/NC(=O)C(=C/3C=C)C

InChI

1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

InChI 密鑰

BPYKTIZUTYGOLE-IFADSCNNSA-N

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本產品
B4126NIST916B14370
胆红素 NIST®SRM®

NIST916B

胆红素

form

solid

form

powder

form

-

form

powder

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

NIST®

manufacturer/tradename

-

storage temp.

10-30°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

-

storage condition

-

solubility

chloroform: 1 mg/mL, alkaline solution: soluble

solubility

aqueous acid: soluble, aqueous base: soluble, benzene: soluble, chloroform: soluble

solubility

-

solubility

-

一般說明

胆红素是橙黄色的胆汁色素[1],是血红蛋白降解的主要代谢终产物之一。[2]含有共轭双键和活泼氢原子。对于成人,正常范围内的胆红素浓度上限为>1mg/dL。[3]新生儿的血清胆红素水平小于15 mg/dl。[4]本品是未结合胆红素。

生化/生理作用

据报道,胆红素可穿过血脑屏障,在脑中发挥重要的抗氧化作用。各种黄疸的变色症状中都有胆红素参与。[1]胆红素水平可作为肝脏和血液病的生物标志物。[5]低浓度的未结合胆红素可作为生理抗氧化剂,[2][5]但胆红素浓度过高会产生毒性,导致新生儿高胆红素血症。[5]

準備報告

碱性溶液中不稳定;临用前复溶。

其他說明

消光系数(454 nm, CHCl3):59,100-62,300 M-1cm-1
细胞渗透性:否
可逆:否
产物不与ATP竞争。
主要靶标

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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James Chen et al.
Molecular cell, 78(2), 275-288 (2020-03-12)
Transcription initiation requires formation of the open promoter complex (RPo). To generate RPo, RNA polymerase (RNAP) unwinds the DNA duplex to form the transcription bubble and loads the DNA into the RNAP active site. RPo formation is a multi-step process
Mirjam Crul et al.
Journal of occupational and environmental hygiene, 17(7-8), 343-352 (2020-07-08)
Many studies into surface contamination of hospital environments have demonstrated that occupational exposure to cytotoxics through the dermal route remains a possible risk. In this study, we assess the actual dermal exposure of the hands of pharmacy technicians and cleaning
E Jiménez et al.
Environmental toxicology and pharmacology, 80, 103464-103464 (2020-08-05)
The identification of substances that prevent or minimize the detrimental effects of ionizing radiation is an essential undertaking. The aim of this paper was to evaluate and compare the radioprotective potential of chlorophyllin, protoporphyrin and bilirubin, with amifostine®, an US
What's in a name? Physiologic and pathologic jaundice: the conundrum of defining normal bilirubin levels in the newborn.
M Jeffrey Maisels
Pediatrics, 118(2), 805-807 (2006-08-03)
Zeng Hong et al.
ACS omega, 5(46), 29903-29912 (2020-12-01)
The reaction of magnesium or zinc amides with alkyl or benzyl halides is an attractive approach to make C-N bonds, especially for electron-poor organic halides. The magnesium-promoted preparation of hindered non-nucleophilic amine (N,N-diisopropylethylamine) from ethyl chloride and zinc diisopropylamide has

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