This antibody is supplied in the form of unpurified polyclonal rabbit serum, for which the exact specific antibody concentration is not determined. However, for polyclonal antiserum, the specific antibody concentrations could range from 1-10 mg/mL serum, but typically range from 1–3 mg/mL serum.
AB2201
抗-mPER1（残基6-21）抗体
serum, from rabbit
同義詞:
Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui, Period, drosophila, homolog of period 1, period (Drosophila) homolog 1, period homolog 1 (Drosophila)
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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human, mouse, rat
技術
western blot: suitable
GenBank登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
mouse ... Per1(18626)
相關類別
1 of 4
本產品 | SAB1400200 | WH0008864M1 | AB2202 |
|---|---|---|---|
| biological source rabbit | biological source mouse | biological source mouse | biological source rabbit |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| antibody form serum | antibody form IgG fraction of antiserum | antibody form purified immunoglobulin | antibody form serum |
| shipped in wet ice | shipped in dry ice | shipped in dry ice | shipped in wet ice |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| technique(s) western blot: suitable | technique(s) indirect immunofluorescence: suitable, western blot: 1 μg/mL | technique(s) immunofluorescence: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL | technique(s) western blot: suitable |
一般說明
136 kDa
该基因是Period基因家族的成员，并在视交叉上核（哺乳动物脑中的主要昼夜节律起搏器）中以昼夜节律模式表达。该家族中的基因编码运动活动，代谢和行为的昼夜节律的组成部分。视交叉上核中的昼夜节律表达在恒定的黑暗中继续进行，并且明/暗周期的变化引起视交叉上核中基因表达的比例变化。该基因的特定功能尚不清楚。在该基因中观察到了选择性剪接。但是，这些变体尚未得到充分描述。
應用
使用经验证可用于WB的抗mPER1（残基6-21）抗体检测mPER1（残基6-21）。
免疫组化：
在全脑上进行了测试（SCN；CT/ZT12的峰值染色）。 需要根据最终使用情况确定最佳工作稀释度。
在全脑上进行了测试（SCN；CT/ZT12的峰值染色）。 需要根据最终使用情况确定最佳工作稀释度。
生化／生理作用
基于序列同源性，可能与果蝇、尼罗罗非鱼和黄金仓鼠反应。 与其他物种的反应性尚未得到测试。
目录#AB2201将识别mPer1的N端。
分析報告
通过蛋白质印迹法对人脑裂解液进行常规测试
法律資訊
GenBank is a registered trademark of United States Department of Health and Human Services
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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Several epidemiological studies suggest a correlation between eating time and obesity. Night eating syndrome characterized by a time-delayed eating pattern is positively associated with obesity in humans as well as in experimental animals. Here, we show that oil intake at
Nobuko Katoku-Kikyo et al.
PLoS biology, 21(12), e3002419-e3002419 (2023-12-04)
Circadian regulation of gene expression is prevalent and plays critical roles in cell differentiation. However, its roles in the reprogramming of differentiated cells remain largely unknown. Here, we found that one of the master circadian regulators PER1 promoted virus-mediated reprogramming
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Most organisms have a circadian system, entrained to daily light-dark cycles, that regulates 24-h rhythms of physiology and behavior. It is unclear, however, how circadian systems function in animals that exhibit seasonal metabolic suppression, particularly when this coincides with the
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