生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
human
製造商／商標名
Chemicon®
技術
immunohistochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... NOS2(4843)
1 of 4
本產品 | N7782 | SAB5700636 | SAB4200766 |
|---|---|---|---|
| antibody form serum | antibody form IgG fraction of antiserum | antibody form affinity isolated antibody | antibody form purified from hybridoma cell culture |
| biological source rabbit | biological source rabbit | biological source rabbit | biological source mouse |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| clone polyclonal | clone polyclonal | clone polyclonal | clone NOS-IN, monoclonal |
| technique(s) immunohistochemistry: suitable, western blot: suitable | technique(s) microarray: suitable, western blot: 1:10,000 using cells extract of murine RAW 264.7 macrophages activated with LPS and IFN-γ. | technique(s) western blot: 1:500-1:2000 | technique(s) flow cytometry: suitable, immunoblotting: 2-4 μg/mL using mouse macrophage RAW 264.7 cell line activated with lipopolysaccharide (LPS) and interferon-γ, immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human pancreas sections |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
一般說明
免疫原
應用
Neuroscience
Oxidative Stress
Immunohistochemistry: 1:2,500-1:6,000 (ABC).
Optimal working dilutions must be determined by end user.
生化／生理作用
外觀
準備報告
法律資訊
免責聲明
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
相關內容
"Redox reactions are powerful chemical processes that involve the reduction and oxidation of proteins and metabolites found in living things. The mechanisms that regulate them are key to maintaining homeostasis and the balance between good health and disease pathology. Oxidative stress is the state where the delicate balance of redox biology is upset, and the pathology of oxidative stress are the cellular consequences to such an imbalance."
"Aging: getting older, exhibiting the signs of age, the decline in the physical (and mental) well-being over time, leading to death. Since the beginning of time, man has been obsessed with trying to slow down, stop, or even reverse the signs of aging. Many have gone as far as experimenting with nutritional regimens, eccentric exercises, fantastic rituals, and naturally occurring or synthetic wonder-elements to evade the signs of normal aging. Biologically speaking, what is aging? And what does the latest research tell us about the possibility of discovering the elusive “fountain of youth”? Many advances in our understanding of aging have come from systematic scientific research, and perhaps it holds the key to immortality. Scientifically, aging can be defined as a systems-wide decline in organismal function that occurs over time. This decline occurs as a result of numerous events in the organism, and these events can be classified into nine “hallmarks” of aging, as proposed by López-Otin et al. (2013). Several of the pathologies associated with aging are a direct result of these events going to extremes and may also involve aberrant activation of proliferation signals or hyperactivity. The hallmarks of aging have been defined based on their fulfillment of specific aging related criteria, such as manifestation during normal aging, acceleration of aging if experimentally induced or aggravated, and retardation of aging if prevented or blocked, resulting in increased lifespan. The nine hallmarks of aging are genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. The biological processes underlying aging are complex. By understanding the hallmarks in greater detail, we can get closer to developing intervention strategies that can make the aging process less of a decline, and more of a recline."
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