生物源
mouse
品質等級
共軛
biotin conjugate
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
monoclonal
物種活性
pig, mouse
物種活性（以同源性預測）
porcine (based on 100% sequence homology), human (based on 100% sequence homology), chicken (based on 100% sequence homology), rat (based on 100% sequence homology)
技術
immunohistochemistry: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... GFAP(2670)
1 of 4
本產品 | MAB3402C3 | MAB360 | FCMAB257P |
|---|---|---|---|
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| Gene Information human ... GFAP(2670) | Gene Information human ... GFAP(2670) | Gene Information human ... GFAP(2670) | Gene Information human ... GFAP(2670) |
| clone monoclonal | clone monoclonal | clone GA5, monoclonal | clone GA5, monoclonal |
| conjugate biotin conjugate | conjugate CY3 conjugate | conjugate - | conjugate PE |
| species reactivity pig, mouse | species reactivity mouse, pig | species reactivity rat, human, mouse, rabbit, chicken, pig, bovine | species reactivity human |
| antibody form purified antibody | antibody form purified immunoglobulin | antibody form ascites fluid | antibody form purified immunoglobulin |
一般說明
50 kDa calculated
Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.
免疫原
Purified glial filament protein (Debus, E., et al. (1983) Differentiation. 25:193-203.)
應用
Anti-GFAP Antibody, Biotin Conjugate detects level of GFAP & has been published & validated for use in IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Developmental Neuroscience
外觀
Protein A purified
Purified mouse monoclonal IgG1 conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.
準備報告
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
分析報告
Control
Mouse adult brain tissue
Mouse adult brain tissue
Evaluated by Immunohistochemistry in mouse adult brain tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected GFAP in mouse adult brain tissue.
Immunohistochemistry Analysis: 1:100 dilution of this antibody detected GFAP in mouse adult brain tissue.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Guo-Qiang Wang et al.
Journal of neuroscience research, 100(10), 1908-1920 (2022-07-08)
The glymphatic system is a recently discovered glial-dependent macroscopic interstitial waste clearance system that promotes the efficient elimination of soluble proteins and metabolites from the central nervous system. Its anatomic foundation is the astrocytes and aquaporin-4 (AQP4) water channels on
Thomas E Mahan et al.
Molecular neurodegeneration, 17(1), 13-13 (2022-02-04)
One of the key pathological hallmarks of Alzheimer disease (AD) is the accumulation of the amyloid-β (Aβ) peptide into amyloid plaques. The apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset AD and has been shown to
Monica Xiong et al.
Science translational medicine, 13(581) (2021-02-19)
The ε4 allele of the apolipoprotein E (APOE) gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD) and greatly influences the development of amyloid-β (Aβ) pathology. Our current study investigated the potential therapeutic effects of the anti-human
Chao Wang et al.
Neuron, 109(10), 1657-1674 (2021-04-09)
The apolipoprotein E (APOE) gene is the strongest genetic risk factor for Alzheimer's disease and directly influences tauopathy and tau-mediated neurodegeneration. ApoE4 has strong deleterious effects on both parameters. In the brain, apoE is produced and secreted primarily by astrocytes
Avital Licht-Murava et al.
Science advances, 9(16), eade1282-eade1282 (2023-04-19)
Transactivating response region DNA binding protein 43 (TDP-43) pathology is prevalent in dementia, but the cell type-specific effects of TDP-43 pathology are not clear, and therapeutic strategies to alleviate TDP-43-linked cognitive decline are lacking. We found that patients with Alzheimer's
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