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Merck

MAB88916

Anti-Fibronectin Antibody

CHEMICON®, mouse monoclonal, 3E3

同義詞:

Anti-CIG, Anti-ED-B, Anti-FINC, Anti-FN, Anti-FNZ, Anti-GFND, Anti-GFND2, Anti-LETS, Anti-MSF, Anti-SMDCF

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分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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產品名稱

Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3, clone 3E3, Chemicon®, from mouse

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

3E3, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FN1(2335)

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1 of 4

本產品
AV41490SAB1405825SAB4200784
species reactivity

human

species reactivity

bovine, dog, sheep, pig, human

species reactivity

human

species reactivity

chicken, rat, human, mouse

biological source

mouse

biological source

rabbit

biological source

mouse

biological source

mouse

clone

3E3, monoclonal

clone

polyclonal

clone

polyclonal

clone

FN-3E2, monoclonal

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

antibody form

culture supernatant

Gene Information

human ... FN1(2335)

Gene Information

human ... FN1(2335)

Gene Information

human ... FN1(2335)

Gene Information

human ... FN1(2335)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

免疫原

Epitope: cell attachment fragment
Purified human-fibronectin from amnion liquid.

應用

Anti-Fibronectin Frag Antibody, cell attachment fragment, clone 3E3 is an antibody against Fibronectin Frag for use in ELISA, WB, IC, IH.
Immunocytochemistry: (5-20 μg/mL) Immunohistochemistry: (5-20 μg/mL) (Not tested on paraffin sections) Immunoblotting: (5-20 μg-mL)

ELISA

Inactivation or inhibition studies in cell culture.

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
ECM Proteins

生化/生理作用

The antibody reacts with human fibronectin and with a peptic fragment (11.5 kD) from human fibronectin (Pierschbacker et al., 1981) comprimising the cell attachment site (Pierschbacker et al., 1981; Pierschabacker et al., 1983, 1984; Hayman et al., 1985; Ruoslahti et al., 1986; Hynes, 1985). It inhibits the attachment of normal rat kidney cells to human fironectin coated plastic surface (Pierschbacker et al., 1981). Binding of the antibody to fibronectin cannot be inhibited by cell adhesion peptides from fibronectin having the sequence Arg-Gly-Asp of Gly-Arg-Gly-Asp-Ser (Pierschabacker et al., 1984; Hayman et al., 1985; Ruoslahti et al., 1986).

外觀

Format: Purified
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.

準備報告

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Manuel L B Palacio et al.
Journal of biomedical materials research. Part A, 100(1), 18-25 (2011-10-06)
Conformational changes of fibronectin (Fn) deposited on poly(methyl methacrylate) and poly(acrylic acid) block copolymers with identical chemical compositions were detected using an antibody-functionalized atomic force microscope (AFM) tip. Based on the antibody-protein adhesive force maps and phase imaging, it was
Oncogenic targeting of BRM drives malignancy through C/EBP?-dependent induction of ?5 integrin.
Damiano, L; Stewart, KM; Cohet, N; Mouw, JK; Lakins, JN; Debnath, J; Reisman et al.
Oncogene null
Bryan A McLendon et al.
Biology, 10(6) (2021-07-03)
Cells respond to extracellular mechanical forces through the assembly of integrin adhesion complexes (IACs) that provide a scaffold through which cells sense and transduce responses to those forces. IACs are composed of transmembrane integrin receptors that bind to extracellular matrix
Tomoko Nagase et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 238(5), 1118-1130 (2009-04-23)
In routine culture, human embryonic stem (hES) cells are maintained on either feeder cells or special culture substrates such as Matrigel. However, to expand hES cells for clinical applications, it is desirable to minimize animal-derived materials in the culture for
Wei Liu et al.
Cell and tissue research, 360(2), 245-262 (2015-02-11)
Cochlear micromechanics and frequency tuning depend on the macromolecular organization of the basilar membrane (BM), which is still unclear in man. Novel techniques in cochlear implantation (CI) motivate further analyses of the BM. Normal cochleae from patients undergoing removal of

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