Adenosine 5′-diphosphate sodium salt is soluble at up to 50mg/mL in H2O. Sodium salts frequently increase the solubility of poorly soluble molecules and compounds.
產品名稱
腺苷-5′-二磷酸 钠盐, bacterial, ≥95% (HPLC)
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O
InChI
1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChI key
XTWYTFMLZFPYCI-KQYNXXCUSA-N
biological source
bacterial
assay
≥95% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear to hazy, colorless
storage temp.
−20°C
Quality Level
Gene Information
human ... HSP90AA1(3320), P2RY1(5028)
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1 of 4
本產品 | A5763 | A5638 | A4386 |
|---|---|---|---|
| biological source bacterial | biological source synthetic (inorganic) | biological source - | biological source bacterial |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder | form powder | form powder | form crystalline |
| assay ≥95% (HPLC) | assay ≥96% | assay ≥95% | assay ≥95% (HPLC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information human ... HSP90AA1(3320), P2RY1(5028) | Gene Information - | Gene Information - | Gene Information - |
Application
5′-二磷酸腺苷钠盐已用作：
- 血小板聚集的阳性对照，用聚焦仪分析纯化解聚素的抗血小板活性。
- 制备原液以进行线粒体应激实验。
- 流式细胞术分析中的阳性对照品，用于研究五聚体C反应蛋白（pCRP）和单体CRP（mCRP）对血小板CD62p（P-选择素）表达的影响。
- 血小板激动剂，刺激血小板聚集。[1]
General description
5′-二磷酸腺苷（ADP）是一种通过 FOF1-ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP也可通过单磷酸腺苷酸（AMP）的腺苷酸激酶催化反应得到。ADP是一种血小板激动剂，由血小板致密颗粒分泌。它通过其与ADP受体P2Y1和P2Y12的相互作用影响血小板活化。ADP在通过ecto-ADP酶转化为腺苷后，通过腺苷受体抑制血小板活化。
存儲類別/等級
11 - Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
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條款
HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.
ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.
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which ADP is readily soluble in water, the sodium salt or the product with out sodium salt
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Is product A2754 FDA approved for use in testing patient samples (Platelet aggregation/function testing) at this time?
1 answer-
No, the product A2754 is not FDA approved for testing patient samples for platelet aggregation/function testing at this time.
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What is the solution stability of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?
1 answer-
ADP sodium salt is stable in solution for several months when stored at pH 7 and at -20 °C. When a solution is stored at pH 7 and 4 °C, the solution is stable for several days. It is unstable in acid.
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What are the spectral properties of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?
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The millimolar extinction coefficient of a pH 7 solution of ADP sodium salt is 15.4 at the absorbance maximum wavelength of 259 nm.
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What is the solubility of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?
1 answer-
ADP sodium salt is soluble in water at a concentration of 50 mg/mL.
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I see that the molecular weight for Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754, on the website does not include sodium, water and solvent content. Why is that?
1 answer-
The amount of sodium, water and solvent for ADP sodium salt will vary from lot to lot. The specific lot information can be found on the certificate of analysis located at our website. To obtain the "true" molecular weight (so that one can calculate the molarity of a solution), the sodium, water and solvent amount must be added to the molecular weight listed on the website.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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