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Merck

A5752

肾上腺色素

>95% purity (HPLC), powder

同義詞:

3-羟基-1-甲基-5,6-二氢吲哚二酮

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經驗公式(希爾表示法):
C9H9NO3
CAS 編號:
分子量::
179.17
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

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產品名稱

肾上腺色素, ≥95% (HPLC)

化驗

≥95% (HPLC)

形狀

powder

顏色

red to brown

εmax

3-4.5 at 485-490 nm in water
9.0-10.5 at 299-304 nm in water

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

−20°C

SMILES 字串

CN1CC(O)C2=CC(=O)C(=O)C=C12

InChI

1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3

InChI 密鑰

RPHLQSHHTJORHI-UHFFFAOYSA-N

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1 of 4

本產品
214515D7008N5625
color

red to brown

color

-

color

pink to very dark red

color

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

assay

≥95% (HPLC)

assay

-

assay

≥95%

assay

>99% (TLC)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

應用

肾上腺色素已被用于研究其对大鼠心脏冠状动脉收缩的影响。[1]

生化/生理作用

肾上腺色素是肾上腺素的氧化产物。[2]它与心脏毒性有关。[3][4]它是一种短寿命的细胞毒性分子,是用于杀死细菌的白细胞反应的一部分。[5]肾上腺色素也被建议用以获得拟精神病作用。[6]它可用于确定超氧化物歧化酶的活性。[7]

相關產品

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
Adrenochrome-induced coronary artery constriction in the rat heart.
Karmazyn M, et al.
Journal of Pharmacology and Experimental Therapeutics, 219, 225-225 (1981)
Janna Shainsky et al.
Applied and environmental microbiology, 75(14), 4711-4719 (2009-05-26)
Enantiopure sulfoxides are prevalent in drugs and are useful chiral auxiliaries in organic synthesis. The biocatalytic enantioselective oxidation of prochiral sulfides is a direct and economical approach for the synthesis of optically pure sulfoxides. The selection of suitable biocatalysts requires
The oxidative metabolism of catecholamines in the brain: a review.
Smythies J and Galzigna L
Biochimica et Biophysica Acta, 1380, 159-159 (1998)

Questions

  1. Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?

    1 answer
    1. This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
      https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005

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