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Merck

D9760

L-(−)-二硫苏糖醇

≥95% (titration)

同義詞:

(−)-Cleland试剂, (2R,3R)-1,4-二巯基-2,3-丁二醇, L-DTT, Cleland手性试剂

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經驗公式(希爾表示法):
C4H10O2S2
CAS 編號:
分子量::
154.25
Beilstein:
2036371
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

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品質等級

化驗

≥95% (titration)

形狀

powder

顏色

white

mp

49 - 51 °C ((120 - 124 °F))

溶解度

H2O: 50 mg/mL, clear to hazy, colorless

儲存溫度

−20°C

SMILES 字串

O[C@@H](CS)[C@@H](O)CS

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m0/s1

InChI 密鑰

VHJLVAABSRFDPM-IMJSIDKUSA-N

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本產品
43819D9163D5545
assay

≥95% (titration)

assay

≥99.0% (RT)

assay

≥99%

assay

≥99.0% (titration)

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

solubility

H2O: 50 mg/mL, clear to hazy, colorless

solubility

H2O: 50 mg/mL, clear, colorless, H2O: freely soluble, acetone: freely soluble, chloroform: freely soluble, diethyl ether: freely soluble, ethanol: freely soluble, ethyl acetate: freely soluble

solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

solubility

H2O: 0.1 M, clear, colorless

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

mp

49 - 51 °C ((120 - 124 °F))

mp

40-43 °C, 41-44 °C (lit.)

mp

40-44 °C, 41-44 °C (lit.)

mp

41-44 °C (lit.)

應用

L-DTT [(2R,3R)-1,4-二巯基-2,3-丁二醇;L-二硫苏糖醇]是具有两个立体中心的手性双齿二硫醇,可用于手性反应的研究。L-DDT被提议作为一种立体选择性还原剂,用于复杂分子中的二硫化物桥。[1][2]

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Julia Schueler et al.
Cells, 8(7) (2019-07-22)
In up to 30% of non-small cell lung cancer (NSCLC) patients, the oncogenic driver of tumor growth is a constitutively activated epidermal growth factor receptor (EGFR). Although these patients gain great benefit from treatment with EGFR tyrosine kinase inhibitors, the
Hermann Bultmann et al.
Antimicrobial agents and chemotherapy, 51(5), 1596-1607 (2007-01-31)
Previous studies have shown that peptides containing the protein transduction domain (PTD) of the human immunodeficiency virus tat protein (GRKKRRQRRR) were effective inhibitors of herpes simplex virus type 1 (HSV-1) entry (H. Bultmann and C. R. Brandt, J. Biol. Chem.
Valérie Robin et al.
Molecular therapy. Nucleic acids, 7, 81-89 (2017-06-19)
Spinal muscular atrophy (SMA) is a recessive disease caused by mutations in the SMN1 gene, which encodes the protein survival motor neuron (SMN), whose absence dramatically affects the survival of motor neurons. In humans, the severity of the disease is
Hiroshi Yao et al.
Langmuir : the ACS journal of surfaces and colloids, 29(21), 6444-6451 (2013-05-03)
We here present a study of cross-linking chemistry of optically inactive monothiol-protected gold clusters by chiral bidentate dithiol with two stereogenic centers, (2R,3R)-1,4-dimercapto-2,3-butanediol (L-dithiothreitol; L-DTT), and explore the impacts of the cross-linking on their chiroptical responses. The pristine protective ligand
Stefan Knoppe et al.
Chimia, 67(4), 236-239 (2013-08-24)
Chiral thiolate-protected gold clusters of atomic precision have gained increasing interest in recent years due to their potential use in catalysis, sensing or bioapplications. While the protection of gold clusters with chiral ligands is a rather trivial task, it was

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