P8908

前列腺素 E₁

synthetic, powder, BioReagent, suitable for cell culture

• 同義詞: (11α,13E,15S)-11,15-二羟基-9-氧代前列-13-烯-1-酸, PGE₁, 前列地尔
• 經驗公式（希爾表示法）: C₂₀H₃₄O₅
• CAS 編號: 745-65-3
• 分子量：: 354.48
• UNSPSC Code: 12352209
• NACRES: NA.77
• PubChem Substance ID: 24898994
• EC Number: 212-017-2
• Beilstein/REAXYS Number: 5294062
• MDL number: MFCD00077860
• Biological source: synthetic
• Form: powder
• Assay: ≥98% (HPLC)

屬性

• 產品名稱: 前列腺素 E₁, synthetic, powder, BioReagent, suitable for cell culture
• form: powder
• InChI: 1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
• InChI key: GMVPRGQOIOIIMI-DWKJAMRDSA-N
• SMILES string: O=C1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1
• biological source: synthetic
• product line: BioReagent
• assay: ≥98% (HPLC)
• potency: 0.25-100 ng/mL
• technique(s): cell culture | mammalian: suitable
• solubility: acetone: 10 mg/mL, clear, colorless
• storage temp.: −20°C
• Quality Level: 200
• Gene Information: human ... PTGER1(5731), PTGER2(5732), PTGIR(5739) ; mouse ... Ptger1(19216), Ptger2(19217), Ptger3(19218), Ptger4(19219)

描述

Application

前列腺素 E1 可用于细胞培养以保护人脐静脉内皮细胞（HUVEC）免受过氧化氢诱导的损伤。

Biochem/physiol Actions

前列腺素E₁（PGE1）有助于松弛海绵体组织。 [1] 有助于保持动脉导管通畅。[2][3]用于治疗勃起功能障碍（ED）。[4]

General description

前列腺素E₁ （PGE1）是血管扩张剂。 [2]

Physical form

粉末-0°C；冷冻储存为工作等分试样，避免反复冻融

安全資訊

• wgk: WGK 1
• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral
• 存儲類別/等級: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves